Tag: natural killer cells

A spatial transcriptomics study of fatal COVID-19 lungs reveals progressive loss of endothelial and immune cells, explosive peribronchial fibroblast expansion, ...

A new review details how the transcriptional repressor PRDM1 orchestrates natural killer cell maturation, effector function, and tumor suppression, with ...

A combined CyTOF and computational modeling study shows that NKG2D signaling and degranulation in human NK cells depend on the ...

MIT engineers have developed lipid nanoparticles that reprogram natural killer cells inside the body to destroy cancerous and autoreactive T ...

Researchers at Tokushima University found that combined TP53 and CDKN2A mutations activate cGAS–STING-mediated antitumor immunity, delaying progression to invasive oral ...

MIT researchers have engineered ligand-directed lipid nanoparticles that reprogram natural killer cells into CAR-bearing cancer killers directly inside living animals, ...

A case-control study in southern China links the HLA-A*11:01-negative/KIR2DS4 Deleted/Deleted immune gene profile to significantly higher pretreatment plasma Epstein-Barr virus ...

Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...

New preclinical research shows that the plant compound coumarin activates natural killer cells, boosts their mitochondrial energy supply, and shrinks ...

Researchers have developed engineered feeder cells derived from induced pluripotent stem cells that prolong the survival and boost the killing ...

In the rapidly evolving landscape of immunotherapy, a groundbreaking approach is emerging that holds transformative potential for pediatric autoimmune diseases. ...

Effective against blood cancers, natural killer cells also may be effective against solid tumors An immunotherapy based on supercharging the ...