SOD1 Aggregates Injected into Brain Fluid Trigger ALS in Mice
Injecting two strains of misfolded human SOD1 aggregates into the cerebrospinal fluid of transgenic mice triggered prion-like aggregation and fatal ...
Tag: misfolded protein
Loop-mimetic vaccine targets misfolded SOD1 and slows ALS-like disease in mice
An engineered loop-mimetic antigen raised antibodies against disease-specific misfolded SOD1 and delayed disease onset in ALS-model mice.
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