Tag: Metastasis

A tumor-specific splice variant of CALD1, driven by the splicing factor hnRNPA1 and acting through the motor protein MYH9, promotes ...

A 58-year-old man developed a solitary brain metastasis from gastroesophageal junction adenocarcinoma thirteen years after curative treatment, a case that ...

New research identifies the secreted protein SRPX2 as a molecular switch that stabilizes the TGF-beta receptor to drive metastasis and ...

A new review in Frontiers in Chemical Biology maps how molecular hydrogen reprograms oncogenic signaling, epigenetics, mitochondrial stress, and antitumor ...

A retrospective study of 329 patients with clinically node-negative oral squamous cell carcinoma examined whether the interval between CT staging ...

Osteosarcoma has long frustrated oncologists. It is the most common primary malignant bone tumor, striking hardest in adolescents, and while ...

A Portuguese reference-centre study of twenty patients shows that low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma, though molecularly related, follow ...

A marine-derived fungal sesterterpenoid called MHO7 suppresses the migration and invasion of triple-negative breast cancer cells by inhibiting the FAK ...

Researchers in Milan have identified MyD88 as a tumor cell-intrinsic switch that sustains a metastasis-competent, integrin-driven cell state in NRAS-mutant ...

New research shows that sustained mechanical confinement inside densely packed tumors activates necroptosis in migratory cancer cells, halting metastasis and ...

Researchers at Lund University have shown that pancreatic cancer cells engineered to survive detachment consistently switch on autophagy and ubiquitin ...

A prospective case-control study reports that circulating regulatory B cells, regulatory T cells, and a broad serum cytokine panel are ...

Researchers found that the long non-coding RNA ATP6V1B1-AS1 promotes ovarian cancer growth and metastasis by binding MAP3K3 and activating the ...

A new review in Molecular Cancer maps the bidirectional crosstalk between deubiquitinases and m6A RNA modification, revealing a coupled regulatory ...

A landmark single-cell and spatial transcriptomics study of 62 pancreatic tumors shows that genetically distinct clones within each cancer drive ...

A single-cell analysis of nearly half a million pancreatic cancer cells shows that continuously evolving clones reshape their DNA to ...

New research shows that stress-induced eIF2α phosphorylation drives stress granule formation that promotes growth and metastasis in oral squamous cell ...

A paired-sample study of 38 melanoma patients reveals that metastases undergo coordinated DNA methylation reprogramming largely independent of driver mutations, ...

A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...

Researchers have re-engineered an acupuncture needle into a minimally invasive device that samples DNA biomarkers directly from lymph nodes for ...