Tag: Liver Fibrosis

A multi-omics study finds that liver fibrosis involves coordinated cell-type-specific metabolic remodeling, and that the phospholipid POPE reduces hepatic stellate ...

A new review maps how disrupted iron homeostasis and ferroptosis drive liver disease, from hereditary hemochromatosis to hepatocellular carcinoma, and ...

A prospective case-control study of 60 Egyptians found that patients with metabolic dysfunction-associated fatty liver disease had higher ferritin and ...

A multicenter retrospective study developed a nomogram using four routine blood parameters that outperformed conventional serum indices for detecting significant ...

A prospective study of 96 patients with chronic hepatitis C found that non-fasting serum asprosin differs by sex but does ...

A cross-sectional Chinese community screening study found that the highest tertile of the glucose-triglyceride frailty index was associated with a ...

A new review builds an evidence-tiered framework for predicting GLP-1 therapy response in fatty liver disease using host genotype and ...

An analysis of 2,238 patients with type 2 diabetes from the National Metabolic Management Center database found that liver fibrosis, ...

A retrospective study of 219 Chinese children with choledochal cysts found that the blood enzyme GGT best discriminated significant liver ...

A new mouse study reports that magnolol protects the liver from high-fat diet injury by suppressing the triglyceride-synthesis enzyme MOGAT1 ...

A critical review finds that Salvia miltiorrhiza compounds can protect hepatocytes and suppress fibrogenic stellate cells, but no single intervention ...

An analysis of about 2,400 adults with biopsy-confirmed MASLD linked early-onset cirrhosis to genetic susceptibility and type 2 diabetes, while ...

A study of 6,773 healthy adults found elevated interleukin-10 and six growth factors in occult hepatitis B, with combined macrophage ...

Preclinical experiments identify kurarinol A as a candidate MyD88-targeting compound that suppresses activated hepatic stellate cells, while animal benefits were ...

A preclinical mouse study found that Gudan Wan reduced liver injury, inflammation and fibrosis while altering autophagy- and apoptosis-related proteins, ...

A Schistosoma japonicum-derived microRNA reduced liver fibrosis in carbon-tetrachloride-treated mice alongside lower stellate-cell activation, collagen deposition and inflammatory signaling.

A new study finds that the Prognostic Nutritional Index and monocyte-to-lymphocyte ratio outperform FIB-4 and APRI for detecting cirrhosis in ...

A new review in Molecular Biology Reports maps how interleukin-24, once known only as a melanoma differentiation gene, regulates hepatocellular ...

A single-cell RNA sequencing atlas of biliary atresia livers reveals expanded pro-inflammatory neutrophil subsets, activated cytotoxic lymphocytes, and injured endothelial ...

Metabolic dysfunction-associated steatotic liver disease, known as MASLD, has quietly become the most common chronic liver condition on the planet, ...