Tag: Liver Fibrosis

A new cross-sectional study of 344 older adults links sarcopenia to a higher prevalence of sonographic fatty liver, though adjusted ...

A new cross-sectional study of 301 patients in Dubai found that vitamin D deficiency is highly prevalent in MASLD and ...

A new review in Nature Reviews Gastroenterology & Hepatology explains how cholangiocyte primary cilia sense bile flow, chemistry and tonicity ...

A new review proposes that lipid metabolism plays fundamentally different roles at each stage of fatty liver disease progression to ...

A Duke-NUS pre-clinical study has created the first diet-induced mouse model of lean MASH, showing that excess dietary salt can ...

A new Nature Communications study shows that the ubiquitin ligase PRPF19 drives hepatic stellate cell activation and liver fibrosis by ...

A pilot study in Brazil found that the Enhanced Liver Fibrosis blood test rises in step with the severity of ...

A 24-week clinical trial in patients with type 2 diabetes and fatty liver disease found that optimal glycemic control, but ...

A new agentic framework uses large language model agents with containerized tools to retrieve, re-quantify, and synthesize published omics data, ...

A large NHANES-based study finds that pro-inflammatory diets roughly double mortality risk in fatty liver disease while antioxidant-rich diets are ...

New research shows that copper accumulation in Wilson disease shuts down the PPARα–FABP1 fat-handling axis in hepatocytes, sensitizing them to ...

A 649,295-cell single-cell atlas of human livers has revealed a pro-inflammatory OLR1-positive scar-associated macrophage population that expands across chronic liver ...

A new Nature Communications study shows that inhibiting the epigenetic enzyme EP300 restores the antibacterial function of scar-associated macrophages by ...

A phase-2 randomized trial shows intermittent dasatinib plus quercetin significantly improved liver fibrosis and resolved MASH in nearly half of ...

A 356-patient Japanese trial found the selective PPARα modulator pemafibrate reduced liver enzymes in a dose-dependent manner and preserved kidney ...

In a groundbreaking development that may redefine our understanding of biliary atresia, researchers Balfour-Lynn and Dhawan have spotlighted the enzyme ...

Tirzepatide, a novel therapeutic agent, has emerged as a beacon of hope for individuals grappling with metabolic dysfunction-associated steatohepatitis (MASH). ...

In a groundbreaking publication that promises to reshape our understanding of liver fibrosis, researchers have uncovered the pivotal role of ...

Liver disease remains a pervasive global health challenge, predominantly triggered by factors such as chronic alcohol consumption, hepatic steatosis linked ...

Cellular senescence represents a fundamental biological phenomenon characterized by the irreversible arrest of the cell cycle, a process initiated in ...