Dietary Vanadyl Sulfate Selectively Eliminates Senescent Cells and Extends Mouse Lifespan
Researchers have discovered that vanadyl sulfate acts as a selective senolytic agent by disrupting vulnerable protein-folding machinery in senescent cells, ...
Tag: Lifespan extension
Dog lifespan drugs offer a roadmap for human gerotherapeutics
A GeroScience commentary argues that veterinary conditional approval frameworks and existing mortality-benefiting drugs could guide human lifespan therapeutics development.
Broccoli compound sulforaphane extends worm lifespan by slowing a transcriptional aging clock
Sulforaphane extended C. elegans lifespan by more than 50% when given early in life and made worms transcriptionally about four ...
Turning Down Insulin Signalling Speeds Worm Development and Extends Lifespan, but Blunts Environmental Sensing
A study of C. elegans shows that developmental insulin signalling knockdown accelerates growth, boosts reproduction and extends lifespan, but impairs ...
Yak collagen peptides inhibit MMP-1 and extend worm lifespan
A computational and experimental study identified three yak bone collagen peptides that inhibited MMP-1 and extended the lifespan of Caenorhabditis ...
Scientists Reverse Aging in Cells and Mice With a Single Gene
Harvard-led researchers developed a transcriptomic aging clock to screen rejuvenation genes and found that over-expressing the RNA splicing factor SRSF1 ...
RNA Splicing Factor SRSF1 Emerges as a Powerful New Regulator of Aging
A transcriptomic reprogramming screen has identified the RNA splicing factor SRSF1 as a conserved regulator of aging that rejuvenates aged ...
Grasshopper Study Reveals the Goldilocks Zone of Leucine Burning for Long Life
A new GeroScience study in lubber grasshoppers shows that intermediate rates of leucine catabolism, measured by carbon-13 breath tracking, are ...
Longer Fat Chains, Shorter Lives: Lipid Elongation Emerges as a Hallmark of Aging
A Nature Aging commentary highlights research identifying lipid acyl-chain elongation as a conserved, causal and potentially reversible hallmark of aging ...
Better Survival in Mice Is Not Proof of Senolytic Anti-Ageing Success, Researchers Warn
A new letter in the Journal of Translational Medicine argues that a senolytic vaccine study showed real therapeutic benefit in ...
Aging Makes Fatty Chains Longer, and Shortening Them Extends Lifespan
A cross-species study in Nature Aging shows that lipid acyl chains lengthen consistently with age across mice, worms, flies and ...
Reducing RAD23A Extends Lifespan in TDP-43 Mice
In a groundbreaking new study published in Nature Communications in 2026, researchers have uncovered a promising therapeutic target that could ...
Reviving Brain Function and Longevity with K+ Channel Modulator
Recent advances in neuroscience have illuminated the intricate connections that sustain brain function, mobility, and overall quality of life. A ...
Extend Your Lifespan: New Insights Revealed
A groundbreaking study from the Max Planck Institute for Biology of Ageing has unveiled compelling evidence that the combined administration ...
Convergent mechanism of aging discovered
Fundamental signaling pathway is crucial for longevity Several different causes of ageing have been discovered, but the question remains whether ...
