Tag: insulin resistance

Researchers have identified the phosphatase DUSP4 as a key activator of fat-cell thermogenesis through dephosphorylation of CRTC3, a mechanism that ...

A large Chinese cohort study found that a higher creatinine-to-body weight ratio, a proxy for muscle mass, was linked to ...

A study of nearly 18,000 Iranian adults found that simple waist- and triglyceride-based indexes, particularly the lipid accumulation product and ...

A new review argues that the evolutionarily conserved IRE1α/XBP1 stress-signaling pathway, which governs protein folding, inflammation and insulin action, offers ...

A 14-year study of over 10,000 young patients at a South Indian diabetes centre shows type 2 diabetes is now ...

A new PLOS Medicine systematic review of 34 studies finds that diet and exercise interventions significantly improve menstrual regularity, waist ...

A new study reports that a combined astaxanthin oil and fish oil complex lowered blood glucose, improved lipid profiles, and ...

NIH researchers argue that dementia may be the late-life manifestation of a systemic failure of energy regulation rather than a ...

A new review argues that insulin receptor signaling is a programmable, context-dependent network that engineered mimetics can selectively retune across ...

A large Chinese cross-sectional study of 7,023 adults with type 2 diabetes finds that a composite index of insulin resistance ...

A study of 420 Brazilian adults links variants in ADRB3, LEPR, FTO and PPARG to metabolic syndrome and shows that ...

A new review in Medical Oncology argues that gut microbial dysbiosis drives systemic inflammation that contributes to both type 2 ...

A large infertility cohort analysis finds anti-Müllerian hormone far outperforms testosterone and novel 11-oxygenated androgens in distinguishing ovarian and menstrual ...

Activating the antioxidant regulator NRF2 suppresses STING-driven inflammation in obese fat tissue, but the effect differs sharply between visceral and ...

A new narrative review in Reproductive Sciences argues that gut microbial dysbiosis, endotoxemia, and chronic low-grade inflammation drive insulin resistance ...

New research in Aging Cell shows that aging disrupts pancreatic alpha cell function, driving hyperglucagonemia and increasing diabetes risk in ...

A new clinical study shows that blocking the enzyme ketohexokinase, the gateway of fructose metabolism, improves fatty liver and insulin ...

A nationwide study of over 12,700 sleep clinic patients in Türkiye found that diabetes is independently linked to a higher ...

A supervised twelve-week exercise programme during chemotherapy for early-stage breast cancer was feasible and safe, with exploratory evidence of cytotoxic ...

A meta-analysis of 28 studies covering 71,882 people finds that individuals with metabolic syndrome have significantly higher levels of the ...