Tag: immunotherapy

A new review details how excess copper induces cuproptosis, a mitochondria-dependent form of cell death that cancer cells are uniquely ...

Children with relapsed leukemia and solid tumors increasingly survive because of a new generation of cancer immunotherapies — CAR-T cells, ...

A Japanese case report documents a remarkable sustained response to nivolumab in a patient whose stage III melanoma recurred as ...

A new review maps the rapid rise of NK cell immunotherapy for solid tumors and warns that its cardiovascular safety ...

High-speed atomic force microscopy reveals that antibody accessibility of PD-L1 on cancer-derived vesicles differs from protein abundance.

Seven real-world cases from a Greek neuromuscular center show how FcRn antagonists, rituximab and ravulizumab can be sequenced in generalized ...

Australian researchers have completed the first head-to-head comparison of three mRNA-lipid nanoparticle vaccine platforms in human blood, revealing key differences ...

A nationwide analysis of 8,104 Hungarian patients treated from 2013 to 2022 shows median survival of just 9.3 months with ...

A biomimetic nanoplatform cloaked in microglial cell membranes delivers carbon monoxide, manganese ions, and Gasdermin E across the blood-brain barrier ...

A new open-source Python package called ROOFS benchmarks multiple feature selection methods on a researcher's own data, evaluating predictive performance ...

A latent profile analysis of 331 lung cancer patients receiving immunotherapy identified three distinct financial toxicity groups, with lower income, ...

A comprehensive systematic review of 49 pre-treatment cohorts identifies circulating protein signatures, including inflammatory markers and T-cell activation ligands, that ...

A new review in Cellular and Molecular Life Sciences maps the molecular pathways, immune microenvironment and AI-driven technologies that shape ...

A new systematic review and meta-analysis finds that starting lenvatinib below 20 mg with pembrolizumab neither clearly preserves tumor response ...

A case report describes how an early-stage esophageal cancer with seemingly low-risk features produced an explosive cervical lymph node recurrence ...

A case report from Gunma University describes severe autoimmune hemolytic anemia triggered by nivolumab plus ipilimumab for melanoma that resolved ...

A systematic review and meta-analysis of 23 studies and 547 patients finds that CD19-directed CAR T-cell therapy delivers encouraging one-year ...

A dual-photosensitizer light treatment combined with optical clearing eradicated thick pigmented melanoma in mice by triggering a potent, long-lasting anti-tumor ...

A comprehensive review maps the engineering, biomarker, manufacturing and economic innovations that will determine whether CAR-T cell therapy can move ...

A phase 1 trial found that the investigational BCMA-targeted CAR-T therapy anito-cel produced responses in all 38 participants with relapsed ...