Tag: immune dysregulation

A study in Frontiers in Molecular Biosciences identifies SERPINB5 and SPAG6 as candidate correlates of idiopathic pulmonary fibrosis pathology, linking ...

A comprehensive narrative review reveals how persistent viral components, immune dysregulation, endothelial injury, and autonomic nervous system dysfunction drive the ...

A new review highlights rezpegaldesleukin, a drug that expands regulatory T cells to treat immune-mediated skin diseases like atopic dermatitis, ...

A retrospective cohort study found that specific composite inflammatory-immune markers are independently associated with 28-day and 1-year mortality in sepsis ...

A computational study identified and validated a three-gene placental signature—FLT1, LEP, and HTRA4—linked to inferred M2 macrophage enrichment that discriminates ...

A study in Arthritis Research & Therapy identifies inflammatory proteins that change years before rheumatoid arthritis symptoms appear, linking these ...

A case-control study of 90 first-episode, drug-naïve schizophrenia patients and 90 matched controls found lower serum BAFF and APRIL in ...

A new bioinformatics and experimental study identifies twelve candidate genes for polycystic ovary syndrome and shows that the metabolic enzyme ...

A study of older adults in the GAINS cohort found higher IL-2 levels in mild frailty and showed inflammatory markers ...

An electronic Delphi consensus of 104 Italian dermatologists reached agreement on 42 of 43 statements defining and managing eczema–psoriasis overlap.

A single-centre Italian study of 21 children with Sjögren’s disease found that 38 percent fulfilled criteria for an ALPS-like immune ...

A perspective in Critical Care argues that pneumonia-associated sepsis should be understood as a multidimensional syndrome driven by loss of ...

A new rat model of ovarian endometrioma combined with single-cell RNA sequencing reveals granulosa cell dysfunction, stromal fibrosis, and immune ...

A narrative review synthesizes evidence that airborne pollutants disrupt immune homeostasis through oxidative stress, epithelial injury and inflammatory signaling, while ...

A review finds that protein modifications regulate immune inflammation and epithelial barrier dysfunction in ulcerative colitis through mechanisms that remain ...

A 69-microRNA signature measured in blood exosomes classified Parkinson's disease with an AUC of 0.952 across cohorts, while multi-omics analyses ...

A review identifies inflammation and immune readjustment as central factors in chemotherapy-related fatigue among breast cancer patients, while noting that ...

A prospective study found that moderate pediatric burns were associated with reduced monocyte HLA-DR expression but heightened early whole-blood TNF-α ...

A case report describes a seven-year-old boy with dystrophy of 19 nails and no eczema whose nails nearly normalized after ...

A new review argues that arsenic-driven immune perturbation is the unifying mechanism behind arsenic-related skin cancers, internal malignancies, and allergic ...