Tag: immune cells

A new study reveals that LCE3D promotes atopic dermatitis inflammation by inhibiting TGF-β1, identifying a potential therapeutic target.

Researchers identified 22 cell-type-specific genetic associations linking immune cell gene expression to epigenetic aging clocks through Mendelian randomization and colocalization ...

A Nature Metabolism review examines how cells balance de novo synthesis and salvage of nucleotides across tissues, immunity and cancer.

A new mathematical model comparing chemotherapy and CAR T-cell therapy for leukemia finds that simulated T-cell infusion produces a stronger ...

A Mendelian randomization study finds that ferroptosis-related genes influence acute myeloid leukemia risk directly and indirectly through specific immune cell ...

A mouse study in The Journal of Immunology reports that hyperglycemia reprograms T cells through an IGF1-IGF1R signaling pathway to ...

An exploratory study derived drug-specific protein signatures from rheumatoid arthritis immune cells ex vivo and found they moderately discriminated treatment-specific ...

An integrated single-cell and spatial transcriptomics study finds CXCR4 concentrated in dermal immune cells of psoriatic skin and identifies a ...

A digital-twin model identified folic acid and aspirin combined with lansoprazole as candidate treatments for delaying preterm labor, without establishing ...

The AI system Unify connected 125 cell types across seven species spanning more than 700 million years by comparing gene ...

A simulation study couples a chaotic three-dimensional tumor growth model with an advanced filtering technique to estimate tumor, host, and ...

An experimental Maynooth University study found that obesity-related defects in Vδ2+ T-cell metabolism and function improved after Roux-en-Y gastric bypass ...

A mouse immune-cell study links inflammation-induced chimeric RNA formation to a functional fusion protein that sharpens the trade-off between bacterial ...

A review in translational medicine outlines how immunologists can design metabolomics experiments and interpret nutrient-tracing data to investigate metabolic regulation ...

StrokeTime integrates 414,359 single-cell transcriptomes from mouse ischemic-stroke studies to trace immune, vascular, glial and neuronal changes from hyperacute injury ...

A new study combines Mendelian randomization with mouse experiments to link specific gut bacteria, including Parabacteroides goldsteinii and Alistipes shahii, ...

A neuronavigation-guided study shows that continuous-time random walk diffusion MRI metrics closely track pathological heterogeneity and immune cell proportions in ...

Researchers have built vascularized, immune-integrated human skin assembloids from stem-cell-derived organoids that model atopic dermatitis-like inflammation and respond to approved ...

In a groundbreaking study published in the Journal of Ovarian Research, researchers Liu, Liu, and Li delve into the complex ...

Genetically engineered immune cells can drive an aggressive type of leukaemia into retreat, a small clinical trial suggests.