Home Transfusions Prove Safe and Feasible for Hospice Blood Cancer Patients
A prospective pilot study shows that symptom-guided home blood transfusions for hospice patients with hematologic malignancies are safe and feasible, ...
Tag: Hematologic malignancies
Blood-based scores and immune biomarkers reshape outcome prediction in blood cancers
A 2026 narrative review synthesizes evidence that inflammatory blood ratios, endothelial scores, and CAR-T-specific tools can stratify outcomes in hematologic ...
Systematic Review Evaluates LSD1 Inhibitors Across Early Blood Cancer Trials
A systematic review of 13 early-phase clinical trials found that lysine-specific demethylase 1 inhibitors show biological activity and disease-specific signals ...
Fever After CAR T-Cell Therapy: New Push for Early Detection of Toxicity
A new review in Blood Research outlines how early detection, risk prediction models, and phenotype-directed treatment are reshaping the management ...
Genetic Study Finds Limited Evidence That Inflammatory Cytokines Drive Blood Cancers
A two-sample Mendelian randomization study of 41 inflammatory cytokines and C-reactive protein found no significant causal effects on selected hematologic ...
Aggressive end-of-life care common in blood cancers, but intensity may not shape dying quality
A multicenter cohort study of 644 hemato-oncology decedents found that most received conventionally aggressive end-of-life care, yet caregiver-reported quality of ...
FDA-Approved Antibody-Drug Conjugates Reshape Blood Cancer Treatment
A new review synthesizes the clinical evidence, toxicity profiles and resistance mechanisms behind six FDA-approved antibody-drug conjugates for blood cancers.
Venetoclax Combinations Show Promise in High-Risk MDS Despite Trial Setback
A narrative review of ASH 2025 and EHA 2026 data suggests venetoclax combinations raise response rates in high-risk myelodysplastic syndromes, ...
Rare eye lymphoma case shows limits of local therapy in NK/T-cell disease
A published case report describes a woman whose EBV-positive NK/T-cell lymphoma relapsed inside her eye and later involved her optic ...
Intrathecal chemotherapy shows early survival gain but no lasting benefit in leptomeningeal disease
A large retrospective database analysis found that intrathecal chemotherapy in leptomeningeal disease was linked to a short-term survival advantage that ...
Caregivers of Older Blood Cancer Patients Carry Heavier Cognitive Burden Than Patients
A cross-sectional survey of 428 patient-caregiver dyads found that primary caregivers of older adults with hematologic malignancies reported significantly higher ...
Educational training tied to higher pediatric palliative care referrals in single-center study
A quasi-experimental study in BMC Pediatrics found that a multimodal educational intervention for pediatric oncologists was associated with referrals among ...
Hidden Monocytosis Clue Reshapes Rare Leukemia Diagnosis in 88-Year-Old Patient
A case report describes how persistent monocytosis documented over more than a year led clinicians to reclassify an 88-year-old man's ...
Retrospective cohort links core biopsy to rare breast blood cancers
A retrospective 24-patient Spanish cohort found that core needle biopsy diagnosed rare hematologic breast malignancies without breast resection in 91.7% ...
Two Gene Signals May Flag Resistance to Standard AML Induction Chemotherapy
Researchers report that elevated expression of the genes TMEM150C and F2R was significantly associated with refractory response to 7+3 induction ...
For Blood Cancer Patients, a Transplant Can Feel Like the Only Choice
A systematic review of 20 qualitative studies finds that blood cancer patients often experience hematopoietic stem cell transplantation as a ...
Big Data Cancer Biomarker Studies Advance Discovery but Await Clinical Validation
Eleven studies using machine learning, single-cell profiling, imaging, liquid biopsy and clinical data identify candidate cancer biomarkers, but retrospective designs ...
HIV-Linked Blood Cancers Strike Younger Patients and Cut Survival, Single-Center Study Finds
A retrospective cohort study of 166 people living with HIV finds that hematologic malignancies strike younger patients, track with high ...
Old Epilepsy Drug Emerges as Safer Seizure Shield for Kids on Chemotherapy
A retrospective study of 19 children with blood cancers suggests topiramate may offer a well-tolerated maintenance antiseizure option during chemotherapy ...
Which Clotting Test Best Predicts Death in Critically Ill Children? A Landmark Study Weighs Five Competing Criteria
A study of 2,015 critically ill children shows that DIC diagnosis varies dramatically across five scoring systems, with sepsis-induced coagulopathy ...
