Dr. Neville Sanjana receives 2020 Cancer Research Institute Technology Impact Award
Grant supports genome engineering study to discover modifier genes that can boost the effectiveness of CAR T-cell therapy for pancreatic ...
Tag: Gene Therapy
A research team of the CNIO and the HKUST identifies how some gliomas develop chemoresistance
Credit: CNIO A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish ...
New understanding of CRISPR-Cas9 tool could improve gene editing
Cryo-EM captures CRISPR-Cas9 base editor in actionCredit: UC Berkeley image by Gavin Knott and Audrone Lapinaite Within a mere eight ...
Novel drug delivery particles use neurotransmitters as a ‘passport’ into the brain
Researchers create neurotransmitter-lipid hybrids that help ferry therapeutic drugs and gene editing proteins across the blood-brain barrier in miceCredit: Qiaobing ...
CZI awards $1.3 million to support the global rare disease community
Grants to NORD and EURORDIS support organizational capacity building and rare disease day campaignsCredit: CZI Today, the Chan Zuckerberg Initiative ...
Un-natural mRNAs modified with sulfur atoms boost efficient protein synthesis
Towards the development of mRNA therapeutics and new methods of protein productionCredit: Nagoya University Since mRNAs play a key role ...
‘Bystander’ Cs meet their match in gene-editing technique
Rice biomolecular engineers' tool sets precisely fix cytosine mutations in human genomeCredit: Gao Lab/Rice University HOUSTON - (July 15, 2020) ...
Genetic editing milestone in mouse model of Rett Syndrome
Editing technique repairs mutant MeCP2 RNA and restores MeCP2 protein functionCredit: Rett Syndrome Research Trust A genomic error that causes ...
Scientists ID gene responsible for deadly glioblastoma
Credit: UVA Health Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery ...
Amygdala changes in male patients with schizophrenia and bipolar disorder
DNA hypermethylation responsible for reduced amygdala volume in male patients with schizophrenia and bipolar disorder.A) CpG site where the structure ...
New Human Gene Therapy editorial: Concern following gene therapy adverse events
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, July 2, 2020--The Editor-in-Chief of Human Gene Therapy, the first journal ...
Off-the-shelf tool for making mouse models of COVID-19
University of Iowa team makes gene therapy approach freely available for COVID-19 researchCredit: University of Iowa Health Care Until there ...
All of Us Research Program launches COVID-19 research initiatives
NIH effort expands data collection to shed light on pandemic's spread and impactCredit: National Institutes of Health The All of ...
Genetic rescue of SHANK3 is potential therapy in rare forms of autism spectrum disorder
A mouse model and previous studies suggest that genetic intervention in SHANK3-related ASD may be most effective earlier in developmentCredit: ...
Researchers model human stem cells to identify degeneration in glaucoma
Credit: IU School of Medicine More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using ...
Reprogramming of immune system cures child with often-fatal fungal infection
UCLA team's approach suggests possible path toward treating other severe infectionsCredit: Nick Carranza / UCLA Health In the June 11 ...
Better detection of a type of ovarian cancer could lead to better treatments
Credit: RCSI Scientists have found that a specific type of ovarian cancer could possibly benefit from existing platinum-based chemotherapy and ...
Scientists aim gene-targeting breakthrough against COVID-19
Cellular delivery system developed at Berkeley Lab's Molecular Foundry could be missing link in battle against SARS-CoV-2Credit: R.N. Zuckermann A ...
Gene therapy with a new base editing technique restores hearing in mice
Repairing a single mutation in the Tmc1 gene restored partial hearing in miceCredit: Olga Shubina-Oleinik, Boston Children's Hospital) Key Findings: ...
A promise to restore hearing
In a first, researchers use base editing to correct recessive genetic deafness and restore partial hearingCredit: Harvard University When Wei ...
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