CNIO researchers develop an effective strategy against KRAS mutant lung tumors in mice
Credit: CNIO The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are directly ...
Tag: Gene Therapy
Genetic study of proteins is a breakthrough in drug development for complex diseases
Credit: Dr Jie Zheng An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology ...
Editing the immune response could make gene therapy more effective
Credit: University of Pittsburgh PITTSBURGH, Sept. 3, 2020 - Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), ...
Two ERC Starting Grants for MDC scientists
ERC funding for pioneering researchCredit: David Ausserhofer/ MDC Dr. Kathrin de la Rosa and Dr. Ilaria Piazza, who are both ...
Toxicity of dorsal root ganglia is widely associated with CNS AAV gene therapy
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, September 2, 2020—A meta-analysis of non-human primate (NHP) studies showed that ...
Gene therapy research for HIV awarded $14.6 million NIH grant
Collaboration co-led by Keck School of Medicine of USC aims for safe, effective treatment inspired by rare cases of HIV ...
Researchers develop a fast, accurate, low-cost COVID-19 test
Credit: NIH Image Gallery, 2018 A new low-cost diagnostic test for coronavirus disease 2019 (COVID-19) quickly delivers accurate results without ...
New book explains DNA for curious nonscientists
"It's complex, but it's not magic"Credit: Alan McHughen After 50 years of research, UC Riverside geneticist Alan McHughen knows what ...
Heart repair factor boosted by RNA-targeting compound
Disney lab collaboration reawakens heart cells' silenced VEGF-A healing system by targeting non-coding RNACredit: Matthew Sturgess for Scripps Research JUPITER, ...
Engineered capsids for efficient gene delivery to the eye
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, August 13, 2020--A rational design approach created novel variants of adeno-associated ...
First in Human Study with Novel Antisense Oligonucleotide
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, August 11, 2020--A single intravenous dose of MRG-110, an anti-microRNA drug, ...
Gene therapy targets inner retina to combat blindness
Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, August 10, 2020--Gene therapy to the inner retina prevented blindness in ...
The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing
Credit: CNIO Idiopathic pulmonary fibrosis is a potentially lethal disease for which there is currently no cure and that is ...
Dr. Neville Sanjana receives 2020 Cancer Research Institute Technology Impact Award
Grant supports genome engineering study to discover modifier genes that can boost the effectiveness of CAR T-cell therapy for pancreatic ...
A research team of the CNIO and the HKUST identifies how some gliomas develop chemoresistance
Credit: CNIO A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumour Group at the Spanish ...
New understanding of CRISPR-Cas9 tool could improve gene editing
Cryo-EM captures CRISPR-Cas9 base editor in actionCredit: UC Berkeley image by Gavin Knott and Audrone Lapinaite Within a mere eight ...
Novel drug delivery particles use neurotransmitters as a ‘passport’ into the brain
Researchers create neurotransmitter-lipid hybrids that help ferry therapeutic drugs and gene editing proteins across the blood-brain barrier in miceCredit: Qiaobing ...
CZI awards $1.3 million to support the global rare disease community
Grants to NORD and EURORDIS support organizational capacity building and rare disease day campaignsCredit: CZI Today, the Chan Zuckerberg Initiative ...
Un-natural mRNAs modified with sulfur atoms boost efficient protein synthesis
Towards the development of mRNA therapeutics and new methods of protein productionCredit: Nagoya University Since mRNAs play a key role ...
‘Bystander’ Cs meet their match in gene-editing technique
Rice biomolecular engineers' tool sets precisely fix cytosine mutations in human genomeCredit: Gao Lab/Rice University HOUSTON - (July 15, 2020) ...