PCOS Gets a New Name and a Radical New Explanation
A major review argues that the newly renamed polyendocrine metabolic ovarian syndrome is a lifelong systems-level disease driven by hypothalamic, ...
Tag: epigenetics
Fish Liver DNA Methylation Reveals Hidden Switches Controlling Egg Development
A new whole-genome bisulfite sequencing study shows that DNA methylation changes in the spotted scat liver are linked to the ...
Lactate’s Hidden Switch: How a Once-Dismissed Metabolite Shapes Brain Repair and Degeneration
A new review in the Journal of Translational Medicine details how lactate and protein lactylation act as a double-edged sword, ...
Quitting Smoking May Rewind Your Biological Clock, Epigenetic Study Suggests
A study of nearly 2,000 US adults found that epigenetic age acceleration from smoking declines steadily after cessation, with former ...
Two Master Genes That Decide Whether Blood Cells Are Born or Turn Cancerous
A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
Epigenetic Clocks Stay Ticking in Brain Fluid After Bleeding Stroke
A longitudinal study of 273 stroke patients shows that DNA methylation age measured in cerebrospinal fluid remains stable after aneurysmal ...
Sperm’s Epigenetic Balancing Act: Flexibility Versus Stability in the Male Germline
A new review in Cellular and Molecular Life Sciences maps how the epigenome of the postnatal male germline balances the ...
How a Shifting Cast of Transcription Factors Rewires Androgen Signaling in the Aging Brain
New research shows that Alzheimer's disease disrupts androgen receptor signaling in the male brain by dismantling the collaborative transcription factor ...
A Methylation Signature in Brain Fluid Predicts Who Survives a Deadly Stroke
Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...
Gene Activity Comes in Bursts: Epigenetics Reshapes the Picture of Transcriptional Noise
A new review argues that transcription occurs in multi-scale bursts shaped by DNA methylation, histone variants, modifications and enhancer looping, ...
Unlocking Genome Methylation with PacBio Long-Read Sequencing
In a groundbreaking study published in Genome Medicine, researchers led by Ivashchenko et al. have unveiled new methods for genome-wide ...
AKT1 Epigenetics Drive Metabolic Shift in Lipedema
Recent research has unveiled significant advancements in our understanding of lipedema, a chronic condition characterized by an abnormal accumulation of ...
Decoding Ageing Tumor Microenvironment’s Genetic and Epigenetic Factors
As we navigate through life, our bodies continuously accumulate somatic mutations that lurk beneath the surface, quietly building a foundation ...
First Episignature Uncovered for Heart Defect Variants
In a groundbreaking study that bridges the fields of genetics and congenital heart defects, researchers have uncovered a significant link ...
Epigenetics and Transcriptomics Reveal Aging Genes
In a groundbreaking study poised to redefine our understanding of human aging, researchers have harnessed the power of integrative epigenetics ...
Maternal Obesity Alters Liver Transcriptomes by Sex
In a groundbreaking study, researchers have identified the existence of sex-specific liver transcriptomes, revealing intricate molecular profiles that evolve during ...
There’s more to genes than DNA: how Mum and Dad add something extra, just for you
Biologists in the UK and Austria have discovered 71 new imprinted genes in the mouse genome Biologists at the Universities ...
Epigenetics has large say in blood formation
Blood stem cells have the potential to turn into any type of blood cell, whether it be the oxygen-carrying red ...
Chronic pain alters how DNA works in brain
Epigenetic changes may be caused by environmental factors, including diet, exposure to contaminants, and social conditions such as poverty—and may ...
