FcRn Blockade Lowers IgG and Alters Amyloid Pathology in Alzheimer’s Model Mice
Blocking the neonatal Fc receptor with efgartigimod reduced circulating IgG and was associated with lower amyloid burden and markers of ...
Tag: efgartigimod
Immunoglobulins and Efgartigimod dampen neuronal activity in rat cortical cultures
Primary rat cortical neurons express FcγRIIb and FcRn, and both immunoglobulins and the FcRn blocker Efgartigimod reduced neuronal activity in ...
Efgartigimod associated with improved daily function in 21 adults with generalized myasthenia gravis; immune findings limited to one patient
A retrospective cohort of 21 adults with acetylcholine receptor antibody-positive generalized myasthenia gravis found improved daily functioning after efgartigimod, while ...
Efgartigimod in generalized myasthenia gravis: new commentary flags post-operative crisis gap
A new commentary on efgartigimod in generalized myasthenia gravis warns that post-operative myasthenic crisis is too often treated as a ...
Fast-Acting Drug Pair Pulls Patient Back From Brink of Myasthenic Crisis
Doctors in China report the first sequential use of efgartigimod and telitacicept to rescue a 73-year-old MuSK-myasthenia gravis patient from ...
Evolution of Primary Autoimmune Neuropathies Explained
Autoimmune neuropathies are a group of rare and disabling disorders, with Guillain–Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) ...
