Tag: DNA Repair

A new study shows the Astragali Radix–Curcumae Rhizoma herb pair synergistically enhances 5-fluorouracil against colorectal cancer by disrupting DNA repair ...

A new perspective article proposes that the body's homeostatic repair mechanisms may prevent everyday non-burning sun exposure from noticeably accelerating ...

In vitro experiments show that TDP2 from mammalian and plant sources can cleave the VirD2 protein from synthetic Agrobacterium T-DNA ...

Preclinical assays found that NU7441 displaced BRD4 from acetylated chromatin and impaired homologous recombination and non-homologous end joining in ovarian ...

A review of preclinical evidence finds that lipid-storage, fatty-acid oxidation, phospholipid and antioxidant programs can influence multiple processes linked to ...

A Molecular Cancer review redefines the MAD gene family as a unified HORMA-domain genome surveillance system linking spindle checkpoint control ...

In the plant pathogen Fusarium mangiferae, ultraviolet C radiation significantly increases ribosome levels and translation capacity in filaments, and blocking ...

St. Jude researchers show the DNA repair enzyme PARP1 evicts two histones near damage sites, forming hexasomes that recruit repair ...

New research shows that inhibiting the ERG protein, overproduced in about half of prostate cancers, selectively impairs DNA double-strand break ...

An observational analysis of 959 prostate tumours from 1,001 men found that eight cellular processes account for 85% of DNA ...

A six-brain sequencing study found that Alzheimer’s-associated tetraploid neurons carried excess low-frequency somatic single nucleotide variants, with enrichment for T>C ...

A whole-genome analysis of 2,157 tumors across 17 cancer types identified distinct deletion patterns associated with two backup DNA-repair pathways, ...

A 2026 review links lactate-driven protein lactylation to glioblastoma growth, stemness, immune escape and treatment resistance in preclinical models, while ...

A University of Ottawa-led cell study found that TONSL recognizes chemical modifications on histone H3.1 to coordinate DNA repair and ...

A modular cytidine base editor that separates its Cas9 nickase and deaminase produced fewer unwanted DNA changes in moss and ...

New research shows that the NarL protein binds directly to the promoter of the DNA repair gene ogt in Salmonella ...

A sweeping narrative review argues that radiation's non-targeted effects, from bystander signaling to biophoton emission and exosome release, are protective ...

The first near-telomere-to-telomere genome of the feather star Cenometra bella reveals unprecedented chromosomal fusion among echinoderms and molecular adaptations that ...

The British Journal of Cancer has retracted a 2014 study linking chromatin structure and DNA repair to chemotherapy outcomes in ...

Researchers in Norway found that children who later develop cancer carry unusual auto-antibodies against their own DNA repair proteins, suggesting ...