Genetic Analysis Links Celiac Disease to Ankylosing Spondylitis Risk
A two-sample Mendelian randomization study indicates that genetically predicted celiac disease may be a potential risk factor for ankylosing spondylitis.
Tag: Causal Inference
Point Grants Boost Digital Spending Without Affecting Cash
A study using large-scale transactional data finds that large point grants increase digital point spending without affecting cash expenditure.
Why standardizing pneumonia response alone cannot define treatment effect in trials
A Critical Care letter argues that standardizing pneumonia response measurement in HAP/VAP does not by itself define the treatment estimand ...
Causal Framework Proposes New Governance for Bias in Clinical Artificial Intelligence
Researchers propose a causal governance framework and multi-agent architecture to distinguish clinically justified contextual differences from harmful algorithmic bias in ...
Forest structure, not just cover, steers water and carbon services
A new review argues that forest structure—not simply forest cover—determines whether management produces synergies or trade-offs among water, carbon, soil, ...
Reporting gaps persist in target trial emulations of type 2 diabetes research
A systematic review of 229 target trial emulation studies in type 2 diabetes finds strong reporting of eligibility, treatment and ...
Big Data’s Big Trap: Why Huge Datasets Can Be Precisely Wrong
A new PLOS Medicine guidance article warns that large biomedical datasets inflate statistical significance while leaving systematic bias intact, and ...
Federated AI Estimates Treatment Effects Without Sharing Patient Data
Researchers have introduced VFCI, a federated framework that trains causal inference models across institutions holding different features of the same ...
Income Tied to Cervical Cancer Survival in SEER Causal Analysis
A SEER analysis of 3,810 cervical cancer patients using marginal structural models and TMLE links low neighborhood income to higher ...
When Two Beeps Trick the Eye: EEG and Bayesian Models Decode a Classic Illusion
A new EEG and hierarchical Bayesian modeling study shows that task conditions dominate perceptual decisions in the sound-induced flash illusion, ...
New Matrices Help Researchers Pick the Right Bias Analysis Method
Researchers built three applicability matrices covering 55 quantitative bias analysis methods to help observational researchers select appropriate bias analysis techniques ...
Genetic Study Finds Limited Evidence That Inflammatory Cytokines Drive Blood Cancers
A two-sample Mendelian randomization study of 41 inflammatory cytokines and C-reactive protein found no significant causal effects on selected hematologic ...
Study Pinpoints Critical Periods That Turn Occasional Gym Visits Into Steady Habits
A large-scale study of Türkiye's biggest gym chain identifies critical attendance periods and shows that personalized guidance and social dynamics ...
From Association to Cause: Review Maps Causal Inference Methods for Alzheimer’s Molecular Data
A new review surveys causal-inference methods applied to Alzheimer's molecular data, finding that many observational associations lack genetic support and ...
Why Experts Sometimes Trust Their Eyes Too Much: A New Model Separates Two Kinds of Multisensory Learning
A new theoretical model separates two distinct forms of multisensory learning, explaining why musicians and wine tasters appear to show ...
Oral microbiome linked to post-surgery aspiration pneumonia in oral cancer patients
A study of 203 oral squamous cell carcinoma patients found that the composition and functional potential of the oral microbiome ...
Predicted outcomes as virtual controls: five conditions for valid treatment effect estimates
Researchers have formally defined the five conditions under which comparing observed outcomes with model-predicted counterfactuals yields valid treatment effect estimates.
How to build clinical prediction models that survive new populations: a scoping review maps the methods
A scoping review of 18 studies categorises the emerging methods for building clinical prediction models that keep their performance in ...
New matching framework weaves polygenic risk into the search for disease causality
A new method called PRIMA incorporates polygenic risk scores into propensity score matching to help disentangle causal disease relationships from ...
When Media Violence Scripts Crime: A New Model Tests Copycat Claims in Psychosis-Associated Filicide
A new hypothesis and theory paper proposes a model and evidentiary protocol for testing when media exposure shapes the form, ...
POPULAR NEWS
-
Imaging Reveals Human Pericyte Fate in Mouse Muscle
-
Water Exchange Rates Reshape Microbiome Dynamics and Ivory Shell Survival in Aquaculture
-
Pediatric Sitosterolemia Cases Reveal Lipid Disorder Mimicking Childhood Rheumatic Joint Disease
-
Dual Bacillus Probiotic Yields Softer Stool and Targeted Immune Shifts in Dogs