Stroke of luck: Scientists discover target for stroke therapy in blood-brain barrier
New study shows that stroke byproduct acrolein activates the precursor of heparanase, an enzyme that degrades the glycocalyx in the ...
Tag: cancer
Oncotarget: MEK inhibitors relevant to SARS-CoV-2 infection
The @Oncotarget authors show a drug class-effect with MEKi to stimulate NK cells, inhibit inflammatory cytokines and block host-factors for ...
Oncotarget: Targeting engineered cytokine with interleukin to the neovasculature of tumors
"The results suggest that this product, or similar fusion proteins featuring an N-terminal fusion in the diabody format, may deserve ...
Oncotarget: MEK is a promising target in the basal subtype of bladder cancer
"The @Oncotarget authors demonstrate that MEK inhibitors are a promising targeted therapy for the basal subtype of bladder cancer, and ...
NYUAD researchers develop high throughput paper-based arrays of 3D tumor models
New technology will help researchers predict the outcomes of drug efficacy and can guide the development of drug treatments for ...
Potentially harmful chemicals found in plastic toys
New research suggests that more than 100 chemicals found in plastic toy materials may pose possible health risks to children.Credit: ...
Discovery of a mechanism by which epithelial tumours cause developmental delays
Credit: IRB Barcelona The systemic balance that coordinates the growth of an organism and its progress through the different stages ...
Advancing understanding of hop genome to aid brewers, medical researchers
Credit: Oregon State University CORVALLIS, Ore. - Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the ...
Scientists model a peculiar type of breast cancer
Credit: George Sflomos (EPFL) Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands ...
New insights on how inflammatory molecule contributes to skin and pancreatic cancers
The molecule, interleukin-33, activates signals in a cell's nucleus to promote abnormal growth.Credit: Jong Ho Park, PhD BOSTON - Chronic ...
New research on mitochondrial function can play significant part in serious disease
Credit: Karolinska Institutet. Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to ...
Turbocharging the killing power of immune cells against cancer
Credit: UHN StRIDe Team Creating "super soldiers" of specific white blood cells to boost an anti-tumour response has been shown ...
Chatter between cell populations drives progression of gastrointestinal tumors
Study results could lead to more effective treatment options for GIST patients, which are currently limitedCredit: UC San Diego Health ...
Neoadjuvant combination immunotherapy improves outcomes for early stage non-small cell lung cancer
Chemotherapy-sparing regimen meets primary endpoint in Phase II studyCredit: MD Anderson Cancer Center HOUSTON -- The first randomized Phase II ...
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