How an unfolding protein can induce programmed cell death
Credit: Sylvia Germes The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. ...
Tag: cancer
Dignity support at end of life
How a two-way approach can promote quality careCredit: Flinders University At the end of life, people may have to rely ...
Chemo upsets gut health in cancer patients
New study challenges role of microbiome disruptionCredit: SA Health and Medical Research Institute (SAHMRI) New research in BMC Cancer has ...
Unraveling the mechanisms that create the individualized metabolism in leukemia
Credit: Associate Professor Shinjiro Hino A research collaboration based in Kumamoto University (Japan) has shown that lysine-specific demethylase 1 (LSD1), ...
Potential drug target for difficult-to-treat breast cancer: RNA-binding proteins
Studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked ...
Development of the world’s first digital model of a cancer cell
With the first cancer cell model, researchers at TU Graz were able to launch an essential tool for modern cancer ...
RESILIENCE, a project to reduce the prevalence of heart failure in cancer survivors
Over one million European cancer patients suffer from side effects to chemotherapyCredit: CNIC Cancer patients are a vulnerable population prone ...
Oncotarget: mTORC1 and PLK1 inhibition in adenocarcinoma NSCLC
All these preclinical data strongly suggest that the inhibition of mTORC1 and PLK1 proteins may be a promising therapeutic approach ...
Using light to treat drug-resistant tumors
National Science Foundation funds investigation of UTA researcher's cancer photodrugCredit: Randy Gentry/UTA A chemist at The University of Texas at ...
Reversal speeds creation of important molecule
Rice's K.C. Nicolaou lab makes synthesis of halichondrin B more efficientCredit: Jenna Kripal/Nicolaou Research Group HOUSTON - (June 29, 2021) ...
Cancer neuroscientists identify a key culprit behind pediatric brain cancer’s spread
ABAT enzyme helps medulloblastoma cells feed, according to study led by USC Brain Tumor Center and Norris Comprehensive Cancer CenterCredit: ...
Cell-based immunotherapy shows promise against melanoma
Effective against blood cancers, natural killer cells also may be effective against solid tumorsCredit: NANCY MARIN/FEHNIGER LAB An immunotherapy based ...
Microfilter device capable of detecting trace amounts of cancer cells in one mL of blood
Top: The device is small enough to fit in the palm of your hand. A microfilter device that can easily ...
Researchers engineer cells to destroy malignant tumor cells but leave the rest alone
Credit: McMaster University HAMILTON, ON June 28, 2021 -- Researchers at McMaster University have developed a promising new cancer immunotherapy ...
Oncotarget: Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
Support recently reported findings of clinical benefit when relacorilant is added to paclitaxel-containing therapy in patients with ovarian and pancreatic ...
Oncotarget: Treatment outcomes in patients with advanced hepatocellular carcinoma
In CTP class A patients, IGF/CTP score B was associated with shorter PFS and OSCredit: Correspondence to - Ahmed O. ...
Oncotarget: Novel markers of colorectal tumors exhibiting microsatellite instability
By incorporating cell composition into their regression model, they identified 3,193 differentially expressed genes, of which 556 were deemed novelCredit: ...
Oncotarget: Predicting clinical outcomes using cancer progression associated signatures
The P142 panel of metrics successfully predicted cancer progression status in patients with some, but not all cancer types analyzed.Credit: ...
Loss of circadian regulation allows for increase in glucose production during lung cancer
New study identifies possible therapeutic target to suppress cancer cell growthCredit: UCI School of Medicine Irvine, CA - June 25, ...
Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
ASU engineering researchers discover and explore new neural stem cell state that gives insight into cancerCredit: Christopher Plaisier/ASU Christopher Plaisier, ...