Tag: cancer progression

A scientific review highlights how oxidative stress drives cancer progression while exposing therapeutic vulnerabilities that can be targeted through synthetic ...

A mini-review in Discover Oncology examines how protein S-palmitoylation exerts context-dependent effects across tumor growth, immune evasion, and cancer therapeutic ...

A new study reveals that RAD18 promotes colorectal cancer progression by degrading SFN, a process regulated by JNK-mediated phosphorylation.

Researchers have identified transcription factor RARG as a candidate tumor suppressor whose loss activates PI3K/AKT signaling via PTHLH downregulation in ...

A scientific review highlights how aberrant mechanical properties in the tumor microenvironment drive cancer progression and therapeutic resistance.

A new integrative bioinformatic study reveals that immune checkpoint and epithelial-mesenchymal transition pathways interact context-dependently to shape the tumor microenvironment ...

A review in Cellular Oncology synthesizes evidence on how primary cilia gain and loss orchestrate therapeutic resistance and metastasis across ...

A new study shows that the circular RNA circCDYL2 stabilizes CDC42 mRNA by recruiting PTBP1, promoting cytoskeletal remodeling that enhances ...

A study in non-small cell lung cancer models found that FBXO28 promotes proliferation, migration and invasion by ubiquitinating BRD4 and ...

New research shows that the extracellular matrix protein LAMB1 accelerates esophageal squamous cell carcinoma by activating JAK2/STAT3 signaling, suggesting it ...

A new evolutionary analysis shows that NOTCH1 mutations flourish in normal esophageal tissue but epistatically suppress the later driver mutations, ...

New research shows that arecoline, the main alkaloid in betel nut, activates a ROS-NRF2-MT2A signaling axis that protects oral squamous ...

New research in The FEBS Journal links mitochondrial DNA copy number in cancer cells to mutational load, tumor growth gene ...

A new systematic review and meta-analysis of 20 human studies finds no consistent association between root canal bacteria and breast ...

Notch signaling is an intricate cellular communication pathway, pivotal in various biological processes, including cell differentiation, proliferation, and apoptosis. Recent ...

Colorectal cancer remains one of the most prevalent malignancies globally, posing significant challenges in terms of early detection, effective treatment, ...

In the intricate realm of cancer research, new findings emerge that could reshape our understanding of head and neck squamous ...

In the rapidly evolving realm of molecular biology, one of the most captivating frontiers is the epitranscriptome—the layer of chemical ...

Recent advancements in cancer research have illuminated a previously underexplored area concerning the role of copper metabolism in malignancies. This ...

A groundbreaking study has illuminated the timeline and growth patterns of chronic myeloid leukaemia (CML), a type of cancer that ...