Oncotarget: The goal of geroscience is life extension
Dr. Mikhail V. Blagosklonny from The Roswell Park Cancer Institute said, 'Although we do not know everything about aging, we ...
Tag: Breast Cancer
Breast cancer-on-a-chip for testing immunotherapy drugs
Credit: Khademhosseini Lab (LOS ANGELES) - There are many mechanisms by which the body responds to foreign invaders. One of ...
Test for early detection of heart problems reduces risk of heart damage from chemotherapy
Credit: Photo: UHN Toronto, ON - Results of a multi-centre, international, clinical trial co-led by Peter Munk Cardiac Centre (PMCC) ...
Imaging identifies breast cancer patients unlikely to benefit from hormone therapy
Findings could help improve treatment decisionsCredit: Farrokh Dehdashti Hormone therapy commonly is given as a targeted treatment for women whose ...
Oncotarget: The pro-apoptotic actions of 2-methoxyestradiol against ovarian cancer
The objective of this Oncotarget study was to elucidate the molecular mechanism of actions of 2MeOE2, a known microtubule disrupting ...
Oncotarget: Simvastatin is a potential candidate drug in ovarian clear cell carcinomas
"Simvastatin efficiently controlled OCCC proliferation and migration, thus showing potential as a candidate drug for the treatment of OCCC."Credit: Correspondence ...
Oncotarget: Neuroendocrine carcinoma of uterine cervix findings shown by MRI
"The Oncotarget author's findings show that MRI is reliable for T staging of cervical NEC"Credit: Correspondence to - Kazuhiro Kitajima ...
Novel therapy-resistance mechanism promoting the growth of breast cancer brain metastasis
Credit: Ilkka Paatero from Turku Bioscience SORLA is a protein trafficking receptor that has been mainly studied in neurons, but ...
Scientists spotted RPS-12 protein as a potential target for anti-cancer therapy
Credit: FEFU press office Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 ...
Nanoparticle drug delivery technique shows promise for treating pancreatic cancer
Method may also work for breast, prostate, ovarian cancerCredit: Jeff Gates Researchers with the Kansas City Veterans Affairs Medical Center ...
A new mechanism protects against cancer cell migration and neuron hyperexcitability
Credit: Christoph Luchs G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in ...
Oncotarget: Drug-resistant cells grow exponentially in metastatic prostate cancer
The Oncotarget authors show that the drug-resistant, metastasis-causing cells are capable of producing drug-resistant, exponentially growing tumors, responsible for tumor ...
Oncotarget: Prognostic biomarker for patients with hepatocellular carcinoma
Reduced expression of TBX15 in tumor tissue represents a potential biomarker for predicting poor survival of patients with HCCCredit: Correspondence ...
Oncotarget: Improved therapeutic efficacy of unmodified anti-tumor antibodies
The Oncotarget findings suggest that MEKi induced an increased expression of tumor-associated antigens, which in combination with anti-tumor antibodies, generated ...