Blocking ELK1 Steadies a Bone-Forming Protein to Boost Stem Cell Repair
In mouse periodontal ligament stem cells, silencing the transcription factor ELK1 reduced STUB1-driven ubiquitin degradation of DLX2, raising osteogenic markers ...
In mouse periodontal ligament stem cells, silencing the transcription factor ELK1 reduced STUB1-driven ubiquitin degradation of DLX2, raising osteogenic markers ...
In rat bone marrow stem cells, the TLR4 inhibitor TAK-242 suppressed LPS-induced inflammatory gene expression while leaving osteogenic differentiation largely ...
An editorial on a Frontiers Research Topic argues that smart biomaterials and additive manufacturing must be tied to measurable, reproducible ...
A collagen hydrogel releasing a T cell-inducing drug enhanced bone regeneration in a rodent skull defect model.
A new review maps how artificial intelligence is reshaping 3D-printed hydrogel scaffolds for skin and bone regeneration, while flagging the ...
A new injectable hydrogel combining boronic ester bonds and boron–nitrogen coordination promoted bone regeneration in a rat calvarial defect model ...
A new review maps how hydrogels engineered to release antibiotics first and growth factors second could integrate infection control and ...
A 3D-printed polycaprolactone sleeve reduced transverse strain in porous gyroid bone scaffolds by 8.2 percent in cadaveric ovine defect tests, ...
A mouse study finds that the collagen receptors β1 integrin and DDR2 cooperate to drive skeletal progenitor cell migration, proliferation ...
A sandwich-structured PVDF and silk fibroin hydrogel laced with MXene converts everyday mechanical stress into electrical stimulation, tipping the bone-fat ...
An agent-based simulation suggests that osteocytes embedded in newly formed bone can retain youthful responsiveness to mechanical loading even in ...
A sustained-release nanofibrous membrane delivered wild-type stem-cell extracellular vesicles to improve bone formation in p75NTR-deficient mouse cells and cranial defects.
A new review examines how piezoelectric biomaterials that convert mechanical force into electrical signals could eradicate bacteria, recalibrate the immune ...
A new review reveals how collagen's intrinsic piezoelectricity could power self-driven tissue regeneration and biosensing implants without external energy.
Macrophage-derived IL-18 triggers inflammatory senescence and feed-forward inflammation that suppresses mesenchymal stem cell osteogenesis, impairing skeletal regeneration in mice and ...
A new review argues that the protein layer acquired by bone implants within seconds of insertion, not the material itself, ...
A comprehensive review finds that nanoparticles synthesized from the medicinal plant Cissus quadrangularis show potent activity against multidrug-resistant bacteria and ...
Researchers at Capital Medical University have identified Id3 as a molecular brake that limits ultrasound-induced bone formation and shown that ...
Researchers have developed a Matrigel-free, aloe vera-containing bioink for 3D-printing bone organoids that recruit and polarize macrophages toward a pro-regenerative ...
Researchers have created an injectable black phosphorus-collagen hydrogel that converts breathing-driven mechanical strain into electrical signals and near-infrared light into ...
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