Tag: biomarkers

A new study shows that the leukaemia gene TET2 directly controls the RNA-regulating protein AGO2, and reducing AGO2 impaired leukaemia ...

Researchers integrating bioinformatics, machine learning, clinical validation and in vitro experiments identified MINPP1, HES4 and SLCO5A1 as core signature genes ...

The Alzheimer’s Association and The Michael J. Fox Foundation created a bridge funding program to support eighteen neurodegenerative research projects ...

The National Multiple Sclerosis Society has launched a funding opportunity to support scalable screening technologies that advance earlier detection of ...

A retrospective cohort study of 2,229 older adults found that a low admission HALP score, calculated from routine blood values, ...

A new review maps how nerve, immune and tumor cell interactions drive pancreatic cancer progression, immune evasion, pain and treatment ...

Pediatric inflammatory bowel disease and functional gastrointestinal disorders exhibit significantly different gut microbial and bile acid profiles that may serve ...

An editorial in Frontiers in Psychiatry highlights how electrophysiological measures can bridge the gap between preclinical neural mechanisms and clinical ...

A study of 409 participants found that sleep-disordered breathing is associated with elevated cerebrospinal fluid markers of blood-brain barrier dysfunction ...

A retrospective study of 102 elderly patients found that the triglyceride–glucose index is significantly elevated in vascular cognitive impairment and ...

A narrative review in Frontiers in Oral Health proposes a staged framework for validating redox biomarkers as tools for longitudinal ...

Researchers developed a Random Forest machine learning model using 11 clinical, molecular, and cytological predictors to stratify individual cervical cancer ...

A review published in Cell Division examines the molecular pathology of microRNA-339, detailing how it predominantly acts as a tumor ...

In a retrospective study of 194 men, computed tomography tissue density measurements in penile segments and splenic parenchyma correlated with ...

A systematic benchmark reveals that biologically structured module representations offer feature stability across breast cancer datasets without consistently outperforming gene-level ...

A cross-sectional cohort study reveals that Alzheimer's disease co-pathology in dementia with Lewy bodies is linked to stage-dependent visual impairments ...

Researchers have identified a four-protein plasma signature associated with macrovascular complications in patients with type 2 diabetes.

A new review argues that most ICU biomarkers still guide treatment rather than select it, and that no true companion ...

A nine-year cohort study reveals that an elevated cholesterol, high-density lipoprotein, and glucose index is significantly associated with new-onset hypertension ...

Researchers developed a contrast-enhanced MRI radiogenomic surrogate reflecting a composite hypoxia, angiogenesis, and epithelial–mesenchymal transition transcriptional state that associates with ...