A nine-year cohort study reveals that an elevated cholesterol, high-density lipoprotein, and glucose index is significantly associated with new-onset hypertension ...
Researchers developed a contrast-enhanced MRI radiogenomic surrogate reflecting a composite hypoxia, angiogenesis, and epithelial–mesenchymal transition transcriptional state that associates with ...
A retrospective clinical study reveals that an elevated neutrophil-to-lymphocyte ratio is independently associated with secondary premature ejaculation, distinguishing acquired from ...
A prospective clinical pilot study found that circulating protein and transcript levels of core NLRP3 inflammasome components were significantly elevated ...
A cross-sectional NHANES analysis found that elevated uric acid-to-HDL cholesterol and neutrophil-to-HDL cholesterol ratios were associated with diabetic kidney disease ...
A large cohort study demonstrates that preoperative hemoglobin glycation index is independently associated with postoperative complications following non-cardiac surgery under ...
A retrospective cohort study finds that an elevated neutrophil percentage-to-albumin ratio independently predicts 28-day all-cause mortality in ICU patients with ...
A retrospective study of 220 acute pancreatitis patients found that exploratory machine learning models utilizing cytokine profiles achieved moderate discrimination ...
A longitudinal plasma proteomics study of 11 glioblastoma patients found that inflammatory cytokines rose after radiotherapy with temozolomide and declined ...
A meta-analysis of eighteen studies found that African American participants had significantly lower tau and neurodegeneration biomarker levels in cerebrospinal ...
Stimuli that disrupt the blood-brain barrier induce human brain endothelial cells to secrete extracellular vesicles carrying both shared and stimulus-specific ...
A scientific review highlights how extracellular vesicles mediate inner ear damage and protection while offering potential biomarker and therapeutic applications ...
A prospective multicenter cohort study evaluates whether plasma-derived extracellular vesicles can predict response to anti-PD-(L)1 therapies in patients with advanced ...
A study identified the upregulated mitochondrial tRNA fragment tRF-21-EXEY0VWUD as a potential serum biomarker with good diagnostic accuracy for gastric ...
A multi-cohort transcriptomic study identified shared genetic biomarkers and immune mechanisms connecting atherosclerosis and lung adenocarcinoma, providing new models for ...
A review outlines how extracellular vesicles contribute to Sjögren's disease pathology while carrying molecular signatures that could serve as non-invasive ...
A Perspective in Nature Reviews Clinical Oncology outlines emerging strategies, including liquid biopsy and artificial intelligence, to detect, monitor, and ...
Researchers developed a four-gene panel that stratifies sepsis patients into distinct immunological endotypes associated with differential mortality risks under hydrocortisone ...
A systematic review details how combining cerebrospinal fluid, blood, and saliva biomarkers establishes an accessible biological framework for diagnosing and ...
An integrative machine learning analysis of public tissue transcriptomic datasets identified a candidate 30-microRNA signature for oral squamous cell carcinoma ...
