Sweet Tooth, Faster Aging: Dietary Preferences Linked to Dementia Risk
A large UK Biobank cohort study finds that a sweet-tooth dietary preference profile is associated with sharply higher dementia risk, ...
Tag: Alzheimer’s disease
AI Maps the Hidden Diversity of Amyloid Plaques Across the Alzheimer’s Brain
Using machine learning on tissue from 84 Alzheimer's disease cases, researchers have mapped six distinct amyloid-beta plaque types across 23 ...
Troubled Cholesterol Particle L5 Linked to Fading Language Networks in Early Cognitive Decline
A new GeroScience study finds that elevated levels of electronegative L5 cholesterol are associated with weakened connectivity in the brain's ...
Trouble Waking Up May Signal Slower Thinking in Older Adults, Study Finds
A study of 461 older adults in the Wisconsin Sleep Cohort found that more severe sleep inertia was associated with ...
AI Reads Brain Scans Two Ways at Once to Gauge Neurological Disease Severity
A new dual-stream deep learning framework fuses spatiotemporal brain activity with dynamic functional connectivity to classify neurological disease severity from ...
Brain Waves and Machine Learning Join Forces to Tell Alzheimer’s and FTD Apart
A new explainable machine learning framework combining EEG signals with clinical data distinguishes Alzheimer's disease from frontotemporal dementia with 89.8 ...
Single-Cell Map Reveals Why Some Cholinergic Neurons Age Faster Than Others
Single-nucleus RNA sequencing of the mouse brain reveals that basal forebrain cholinergic neurons undergo uniquely damaging stress-related transcriptional changes with ...
Lithium Deficiency May Drive Alzheimer’s Brain Energy Failure, Review Argues
A new review in BMC Medicine proposes that endogenous lithium deficiency worsens Alzheimer's disease by undermining cerebral energy metabolism and ...
Lactate’s Hidden Switch: How a Once-Dismissed Metabolite Shapes Brain Repair and Degeneration
A new review in the Journal of Translational Medicine details how lactate and protein lactylation act as a double-edged sword, ...
AI Reads Brain Scan Sequences to Spot Alzheimer’s With New Hybrid Model
Researchers in India combined EfficientNet-B0 and a transformer encoder to classify Alzheimer's disease from multi-slice MRI scans, achieving 88 percent ...
Chemical Tags on Blood Proteins Reveal a New Window Into Alzheimer’s Disease
Researchers at the University of Tokyo have produced the first map of lysine acetylation marks across plasma proteins in Alzheimer's ...
How a Shifting Cast of Transcription Factors Rewires Androgen Signaling in the Aging Brain
New research shows that Alzheimer's disease disrupts androgen receptor signaling in the male brain by dismantling the collaborative transcription factor ...
YouTube’s Alzheimer’s Videos Are Mostly Reliable, But Caregivers Are Left Behind
A systematic analysis of 90 Korean-language YouTube videos found that half offered good or excellent Alzheimer's disease information, yet practical ...
Coumarin-1,3,4-Oxadiazole Conjugates Target Alzheimer’s Disease
Alzheimer’s disease poses an increasingly pressing public health challenge, affecting millions worldwide. With an aging population and no available cure, ...
Genetic Risk Factors for Alzheimer’s in Healthy Aging
In an intriguing new study, researchers have delved deep into the intricate relationship between polygenic risk factors for Alzheimer’s disease ...
New Aβ-Tracking PET Radiotracer Revolutionizes Imaging in Monkeys
In groundbreaking developments within the field of neuroimaging, a recent study introduces a novel radiotracer that has shown promise in ...
Exploring Metal Chelation in Anti-AD γ-Pyranones
In an intriguing advance in the pursuit of effective treatments for Alzheimer’s Disease (AD), a recent study led by a ...
Sex Differences in Energy Demand in Alzheimer’s Mice
In groundbreaking research published in the journal Biology of Sex Differences, a team of scientists, including Sun, Zimbalski, and Schreyer, ...
Astrocytic Sox9 Boosts Aβ Clearance, Preserves Memory
In the relentless quest to combat the debilitating effects of Alzheimer’s disease (AD), a new frontier has emerged, spotlighting the ...
Microglial CARs Enhance Selective Phagocytosis of Aβ1-42
In recent groundbreaking research, scientists led by Heiss, C.N., Riise, R., and Hanse, E., published an essential study that sheds ...
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