Tag: acute myeloid leukemia

A new open-access study shows that pseudolaric acid B binds ACTN4, disrupting TfR1 recycling and driving iron-dependent ferroptosis in acute ...

A single-center retrospective study of 32 elderly patients reports high remission rates and manageable toxicity with a response-adapted reduced-dose azacitidine-venetoclax ...

An FDG-PET/CT scan in a 64-year-old woman with fever of unknown origin revealed diffuse osteosclerosis and osteolytic lesions that led ...

A retrospective Korean study found that combining sequencing-based residual disease testing with donor chimerism assessment three months after transplant stratified ...

A BMC Medicine debate article argues that T cells in acute myeloid leukemia are not uniformly dysfunctional and that assessing ...

A machine-learning pipeline identified AML-selective small molecules and implicated glutathione reductase as a vulnerability that can be exploited in laboratory ...

A phase 2 randomized trial found fewer adverse events with daily oral vitamin C in people with pre-leukemia blood disorders, ...

An animal study by City of Hope researchers shows that modular CAR T cells can accept engineered adaptors after treatment, ...

A five-year National Cancer Institute grant will support efforts to identify biomarkers that predict response and relapse in older adults ...

Research reveals that FDX1 downregulation in acute myeloid leukemia drives resistance to cuproptosis via the ROS/p53/ME1 axis, suggesting a new ...

A case report and literature review describe acute myeloid leukemia developing 32 months into icotinib therapy for EGFR-mutated lung cancer, ...

Researchers report that elevated expression of the genes TMEM150C and F2R was significantly associated with refractory response to 7+3 induction ...

A comprehensive review finds that AML cells commonly overcome epigenetic drugs through compensatory chromatin and transcriptional adaptation, favoring biomarker-selected combinations ...

An integrated transcriptomic and laboratory study linked coagulation-associated gene activity to survival and immune states in acute myeloid leukemia, while ...

MSIPep combines immunopeptidomics, transcriptomics and deep learning to identify and computationally prioritize candidate tumor peptides in leukemia and solid-tumor datasets.

A new review details how acute myeloid leukemia remodels the bone marrow microenvironment to shelter both bulk blasts and leukemic ...

A large international study finds that performing stem cell transplants soon after high-risk bone marrow features emerge dramatically improves survival ...

Single-cell sequencing reveals that self-derived and donor-derived exhausted T cells in acute myeloid leukemia run on different transcriptional programs, with ...

A Swedish study found that intensively treated acute myeloid leukemia patients managed at home through a hospital-at-home program spent half ...

A new study of microbial RNA in the blood of leukemia patients suggests that the circulating metatranscriptome may carry information ...