Tag: acute myeloid leukemia

A new two-step machine-learning framework called CLIMB and CLIFF computationally deconvolves bulk RNA-seq and drug sensitivity data into cell-type and ...

A 13-year Polish study of 219 acute myeloid leukemia patients shows that stopping fluoroquinolone prophylaxis in 2018 was clinically safe, ...

A Bulgarian real-world economic model finds that venetoclax plus azacitidine improves survival and quality of life in older AML patients ...

A global meta-analysis of 120 studies finds vancomycin-resistant enterococci in 18.4 percent of patients with haematological malignancies, with prevalence approaching ...

Vienna researchers developed the bicon-seq method and discovered that the long non-coding RNA Gas5 is a functional component of leukemia-driving ...

New research shows that the surface protein CD7 actively drives chemotherapy resistance in acute myeloid leukemia by amplifying NF-κB signaling, ...

A newly reported leukemia case carrying both the rare DEK::CAN fusion gene and WT1 overexpression reveals how genetic synergy and ...

A systematic review in Medical Oncology details how the HUSH complex silences retrotransposons through H3K9me3 deposition and how its dysregulation ...

A comprehensive multi-omics study catalogues thousands of cancer-specific isoform switches in melanoma, ovarian cancer, and AML, showing that most disrupt ...

Researchers have functionally characterized CD34/CD123/CD25/CD99-positive leukemic progenitor cells in FLT3-ITD-mutated AML, showing they engraft and reinitiate leukemia in mice and ...

A new study reports that the circadian clock gene BMAL1 and the cell cycle checkpoint regulator WEE1 are significantly downregulated ...

NIH has awarded its Director's Pioneer Award to Sylvester Comprehensive Cancer Center virologist Leor Weinberger for developing an evolving oncolytic ...

A new Nature Chemical Biology study reveals that the ubiquitin ligase RLIM tags the m6A writer METTL14 with noncanonical K27-linked ...

A systematic review of nine studies finds that therapy-related myeloid neoplasms after CAR-T therapy emerge earlier and carry worse survival ...

A new conditional knockout mouse model shows that loss of the epigenetic regulator Tet2, combined with aging and a reshaped ...

Egyptian researchers have developed and validated a green gradient reverse-phase HPLC method that simultaneously measures cytarabine and granisetron in spiked ...

A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...

In groundbreaking new research published in BMC Cancer, scientists have unveiled intricate molecular dynamics orchestrated by decitabine, a widely used ...

In recent advancements within the realm of hematologic malignancies, researchers have shed new light on the intricate regulatory disruptions driving ...