• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Monday, September 1, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Self-reported declines in cognition may be linked to changes in brain connectivity

Bioengineer by Bioengineer
June 22, 2021
in Health
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Wayne State University

DETROIT – Jessica Damoiseaux, Ph.D., an associate professor with the Institute of Gerontology at Wayne State University, recently published the results of a three-year study of cognitive changes in older adults. The team followed 69 primarily African American females, ages 50 to 85, who complained that their cognitive ability was worsening though clinical assessments showed no impairments. Three magnetic resonance imaging scans (MRIs) at 18-month intervals showed significant changes in functional connectivity in two areas of the brain.

“An older adult’s perceived cognitive decline could be an important precursor to dementia,” Damoiseaux said. “Brain alterations that underlie the experience of decline could reflect the progression of incipient dementia and may emerge before cognitive assessment is sensitive enough to detect a deficit.”

The resulting paper, “Longitudinal change in hippocampal and dorsal anterior insulae functional connectivity in subjective cognitive decline,” appeared in the May 31 issue of Alzheimer’s Research & Therapy. Damoiseaux conducted the study with graduate student Raymond Viviano, Ph.D., who is first author.

Subjective cognitive decline, defined as a perceived worsening of cognitive ability not noted on clinical assessment, may be an early indicator of dementia. Previous cross-sectional research has demonstrated aberrant brain functional connectivity in subjective cognitive decline, but longitudinal evaluation has been limited.

Viviano and Damoiseaux’s three-year study found that persons reporting more subjective cognitive decline showed a larger decrease in connectivity between components of the default mode network and a larger increase in connectivity between salience and default mode network components. The functional connectivity changed in the absence of a change in cognitive performance.

Since these brain changes occurred without concomitant cognitive changes, they could indicate that brain changes underlie the perception of decline. These changes could be a sensitive marker for nascent dementia months or years before assessments detect any cognitive deficit.

###

About the Institute of Gerontology

The Institute of Gerontology researches aging, trains students, and informs professionals, caregivers and older adults on aging (iog.wayne.edu). It is part of the Division of Research at Wayne State University.

Media Contact
Julie O’Connor
[email protected]

Original Source

https://research.wayne.edu/news/self-reported-declines-in-cognition-may-be-linked-to-changes-in-brain-connectivity-42750

Related Journal Article

http://dx.doi.org/10.1186/s13195-021-00847-y

Tags: AgingGerontologyMedicine/HealthMemory/Cognitive ProcessesMental HealthSocial/Behavioral Science
Share12Tweet8Share2ShareShareShare2

Related Posts

Comparing Titanium and PEEK Intervertebral Fusion Techniques

September 1, 2025

Advancements in EEG-Based Brain-Computer Interfaces in Medicine

September 1, 2025

Sustainable Nursing Leadership: Harnessing Knowledge for Change

September 1, 2025

Melatonin Shields Ovaries from LPS-Induced Damage

September 1, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    153 shares
    Share 61 Tweet 38
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    143 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    117 shares
    Share 47 Tweet 29
  • Do people and monkeys see colors the same way?

    112 shares
    Share 45 Tweet 28

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Comparing Titanium and PEEK Intervertebral Fusion Techniques

Advancements in EEG-Based Brain-Computer Interfaces in Medicine

New Insights into Pediatric Hypertriglyceridemia Causes

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.