• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Saturday, August 2, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Phantom limb sensation explained

Bioengineer by Bioengineer
February 21, 2019
in Health
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

New study reveals functional changes among sensitive and motor brain areas after limb amputation, shedding light on the mechanisms behind the false idea that the limb is still present.

After a limb amputation, brain areas responsible for movement and sensation alter their functional communication. This is the conclusion of a new study published today in Scientific Reports. According to the authors, from the D’Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ), the findings may help to understand why some patients report phantom sensations and others do not.

Entitled “Lower limb amputees undergo long-distance plasticity in sensorimotor functional connectivity”, the study represents a step forward a complete comprehension of a phenomenon called brain plasticity, which means the brain’s ability to change itself in response to daily life situations. This ability is greater during the early stages of development but is still critical for learning, memory and behavior throughout our whole life. Investigating the underpinnings of brain plasticity is the key to develop new treatments against mental disorders.

In order to go deeper on that, neuroscientists from Brazil decided to investigate the brain after lower limb amputation. In a previous study from the group, a magnetic resonance imaging experiment revealed that the brain overreacts when the stump is touched. Also, they found that the corpus callosum – brain structure that connects cortical areas responsible for movement and sensations – loses its strength. These findings have raised curiosity about what would be the impact of an impaired corpus callosum on the cortical areas it connects.

Led by Fernanda Tovar-Moll, radiologist and president at IDOR, researchers investigated the differences in functional connectivity (i.e. the communication of brain areas) among motor and sensitive areas connected by the corpus callosum in nine lower limb amputees and nine healthy volunteers.

The results showed that authors’ idea was correct: in response to the touch in the stump, sensitive and motor areas of patients’ brains exhibited an abnormal pattern of communication among the right and left hemispheres, probably as a consequence of impaired corpus callosum. In addition, sensitive and motor areas of the same hemisphere showed increased functional communication in amputees.

“The brain changes in response to amputation have been investigated for years in those patients who report the phantom limb pain. However, our findings show that there is a functional imbalance even in the absence of pain, in patients reporting only phantom sensations”, explains Ivanei Bramati, medical physicist and Ph.D. student at IDOR.

According to the authors, understanding the changes of neural networks in response to the amputation can pave the way for the development of new technologies and devices to treat this disorder and offer patients a better quality of life.

###

Reference

Ivanei E. Bramati, Erika C. Rodrigues, Elington L. Simões, Bruno Melo, Sebastian Hoefle, Jorge Moll, Roberto Lent & Fernanda Tovar-Moll. Lower limb amputees undergolong-distance plasticity in sensorimotor functional connectivity. Scientific Reports, volume 9, Article number: 2518 (2019).

Media Contact
Catarina Chagas
[email protected]
55-213-883-6000

Related Journal Article

https://www.nature.com/articles/s41598-019-39696-z#article-info
http://dx.doi.org/10.1038/s41598-019-39696-z

Tags: Medicine/HealthneurobiologyPainPhysiologyTrauma/Injury
Share12Tweet7Share2ShareShareShare1

Related Posts

Magnesium Implants Boost Bone-Immune Health In Vitro

Magnesium Implants Boost Bone-Immune Health In Vitro

August 2, 2025
GBA1 Variants’ Impact on Parkinson’s: In Silico Analysis

GBA1 Variants’ Impact on Parkinson’s: In Silico Analysis

August 2, 2025

Deep Learning Advances MRI Diagnosis of Brucella

August 2, 2025

Predicting Lung Infections After Brain Hemorrhage

August 2, 2025
Please login to join discussion

POPULAR NEWS

  • Blind to the Burn

    Overlooked Dangers: Debunking Common Myths About Skin Cancer Risk in the U.S.

    60 shares
    Share 24 Tweet 15
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    42 shares
    Share 17 Tweet 11
  • Dr. Miriam Merad Honored with French Knighthood for Groundbreaking Contributions to Science and Medicine

    46 shares
    Share 18 Tweet 12
  • Study Reveals Beta-HPV Directly Causes Skin Cancer in Immunocompromised Individuals

    38 shares
    Share 15 Tweet 10

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

TrueBeam vs. Halcyon: Breast Cancer Radiotherapy Comparison

Magnesium Implants Boost Bone-Immune Health In Vitro

Unmet Supportive Care Needs in Cancer Patients

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.