Bile Acid Accumulation Promotes Breast Cancer Spread, Study Finds
A dysregulated gut microbiome can reshape bile acid biology in ways that help hormone receptor-positive (HR+) breast cancer spread, according to new University of Virginia...
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Targeted Nanoparticles Make Tumors’ Copper Into a Lethal Weapon
A new preclinical study in Biomedical Analysis reports a targeted nanomedicine strategy that tackles a long-standing obstacle in copper-dependent cancer therapy. The approach focuses on...
Event-Based Denoising Enables High-Fidelity Fast Fluorescence Lifetime Imaging
Fluorescence lifetime imaging microscopy (FLIM) can reveal how molecules behave in their native environments, including protein conformations, intermolecular interactions and micro-scale biochemical changes. Yet traditional...
Gαq Activates Free Fatty Acid Receptor 4 to Suppress Metabolic Dysfunction
In a study poised to reshape how scientists think about diet-linked metabolic disease, researchers report that activating free fatty acid receptor 4 (FFAR4) can meaningfully...
Iran experts build framework to assess older adults’ primary healthcare access
A new expert-based qualitative study is reshaping how researchers measure whether older adults can actually reach primary healthcare in Iran. Published in BMC Geriatrics, the...
Piperazine Derivatives Trigger Mitochondrial Dysfunction and Microtubule Changes in Neurons
A new study in BMC Pharmacology and Toxicology reports that certain piperazine derivatives can damage neuronal cells through a two-pronged mechanism: mitochondrial dysfunction and microtubule-linked...
Local Neural Operators Enable Equation-Free Analysis of Complex Systems
Neural operators (NOs) are gaining traction as flexible tools for learning the dynamics of complex systems. By framing spatiotemporal evolution as mappings between infinite-dimensional function...
Spontaneous Creation and Optical Control of Woven Domain Patterns in Ferroelectrics
A new study in Light: Science & Applications reports that a ferroelectric crystal can spontaneously generate a striking “woven” pattern of electric polarization domains—and that...
Studying Links Between Loneliness, Social Isolation, and Human Health
A new study in Nature Communications is sharpening the spotlight on a trio of connected outcomes—loneliness, social isolation, and health—using data designed to separate how...
Agroecological Systems Could Prevent Food Systems From Damaging Global Commons
Science, technological innovation, and farmer ingenuity could, in principle, reshape food systems faster than ever. Yet real-world change often stalls because powerful technological pathways become...
Atoco Inc. Launches Reticular Science Prize for Emerging Scholars and Innovators
The Nobel Prize in Chemistry for 2025, recognizing advances in metal-organic frameworks (MOFs), has thrust reticular materials into the global spotlight. MOFs—crystalline solids assembled from...
Kansas City University Review Identifies Astrocytes as Drivers of Chronic Traumatic Encephalopathy
Chronic traumatic encephalopathy (CTE) develops after repeated head impacts and traumatic brain injuries, most often reported in contact-sport athletes and military personnel. For years, the...
Background-Free Adaptive Optics Phase Imaging Using Surface Plasmon Holographic Microscopy
A new microscopy approach is turning phase imaging into a more practical, “background-free” task by merging adaptive optics with surface plasmon resonance (SPR) holography. In...
Survival in Adults With Congenital Heart Disease Linked to Specialized Care Access
A new independent analysis in the Journal of the American Heart Association links state-level socioeconomic conditions with long-term outcomes for adults living with congenital heart...
Regulatory and Analytical Challenges in Quality Assessment of Peptide Drugs
A new review is shaking up how peptide drugs should be judged for quality, arguing that the science of manufacturing is inseparable from the science...