Altered bone marrow niche creates innate immune memory linked to heart dysfunction
A new study has identified the bone marrow as a possible command center for a form of immune memory that can continue damaging the heart...
NEWS INDEX
Long-Term Outcomes for Children After Tetralogy of Fallot Repair
Tetralogy of Fallot was once regarded primarily as a childhood surgical problem: close the holes, relieve the obstruction to blood leaving the right ventricle, and...
Device Logs Reveal Outflow Graft Obstruction After EVAHEART2 Implantation
A rare and potentially fatal complication of long-term mechanical heart support has drawn attention to an overlooked source of clinical evidence: the digital log produced...
Brain regions linked to learning precise finger force control
Writing, buttoning a shirt, picking up a coin or holding a utensil may look effortless, but each action depends on the brain’s ability to regulate...
cGAS-Deficient Mice Show Premature Aging Linked to LINE1 Derepression and Inflammation
A new study published in Nature Aging reports that mice lacking the enzyme cGAS develop signs of premature aging, accompanied by the abnormal activation of...
USP30-AS1 micropeptide drives tumor growth by suppressing macrophage cGAS–STING interferon signaling
Immune checkpoint inhibitors have transformed cancer treatment by releasing molecular brakes that otherwise restrain T cells, yet their benefits remain uneven. Many tumors contain T...
High-Sensitivity Troponin I Adjusted for Heart Mass Detects Stable Coronary Disease
For decades, clinicians have relied on cardiac troponin as the central biochemical signal of heart-muscle injury. When troponin levels rise sharply, the result can point...
Triple-Energy-Transfer Cascade Converts Bicyclic Azaarenes into Complex Dearomatized Molecules
A new study is turning one of organic chemistry’s most familiar ideas—the stability of aromatic rings—into the starting point for a molecular transformation with strikingly...
DREAMS Maps Spatial DNA and RNA Modification Landscapes
A new method reported in Nature Cell Biology is offering scientists an unusually detailed view of how chemical modifications are distributed across DNA and RNA...
Animals Degrade Microbial Polyhydroxyalkanoate Storage Materials
A hidden link between microbial chemistry and animal nutrition has emerged from a study published in Nature Ecology & Evolution, revealing that animals can break...
DDx-PRS Distinguishes Among Psychiatric Disorders
Psychiatric diagnosis may soon become less dependent on drawing rigid boundaries between disorders that frequently overlap in symptoms, biology and treatment response. A new study...
Mapping When and Where Conflict-Related Sexual Violence Occurred in Colombia
Conflict-related sexual violence in Colombia did not follow a uniform geographic or historical pattern, according to a new study that maps how reported incidents shifted...
Progenitor T Cells Fuel Chronic Type 2 Inflammation in the Lungs
A previously underappreciated population of immature T cells may help explain why type 2 inflammation in the lungs can persist long after its initiating trigger...
Krypton-Sputtered Tantalum Films Enable Scalable, High-Performance Quantum Devices
Superconducting quantum technology has just taken a significant step toward becoming easier to manufacture at scale. Researchers have demonstrated that tantalum thin films suitable for...
ProteinDPO Aligns Protein-Generating Models with Experimental Fitness Measurements
Proteins are often described as the machines of biology, but designing one from scratch remains an extraordinary challenge. A sequence of amino acids must fold...
