New antimicrobials may help combat deadly drug-resistant infections
Researchers from Imperial College London and the University of Manchester report a strategy to engineer next-generation antifungals that are both more potent and less toxic...
NEWS INDEX
AI Tool Acts Like a Molecular Shrink Ray, Redesigns Proteins Reliably
Duke University School of Medicine researchers have unveiled Raygun, an artificial intelligence framework that can redesign proteins at a scale reminiscent of natural evolution. Unlike...
Nanjing University Team Proposes PIEM Concept to Transform Microbiome Research
A July 20, 2026 review in Immunity & Inflammation reframes microbiome science by proposing a hidden population: persistent intracellular extraintestinal microbes, or PIEMs. Led by...
Rational Design of Disordered Proteins Enables Sequence-Function Investigation
Intrinsically disordered proteins (IDRs)—segments that do not adopt a single stable 3D structure—are common across life and perform crucial cellular jobs. Yet while scientists can...
Short ACE2 Isoform Increases in Adipose Tissue of Women With Obesity
A recent study adds a new piece to the emerging map of ACE2 biology—an essential entry point exploited by SARS‑CoV‑2 for infection. Researchers report that...
Mitochondria plaques in Alzheimer’s linked to buildup and lysosomal dysfunction
New evidence links a failure of cellular cleanup to the distinctive brain damage of Alzheimer’s disease. In a study in Nature Neuroscience, researchers used an...
Gut Microbiota Limits Intestinal Fat Uptake by Altering Bile Phosphatidylcholine in Mice
A new study adds weight to a growing idea: the gut microbiome doesn’t just digest food—it can actively regulate how the body stores and absorbs...
Conformations of Neuronal Na+, K+-ATPase Isoforms and a Disease-Causing Variant
A new viral-science report spotlights how a pair of neuronal ion pumps—neuronal Na⁺,K⁺-ATPase isoforms—switch between distinct active shapes, and how one disease-associated mutant disrupts that...
Process Mapping Informs Design Strategies to Curb Inappropriate HFNC Use
Emergency departments facing bronchiolitis in infants often rely on high-flow nasal cannula (HFNC) oxygen therapy, a tool that can help when respiratory distress escalates. Yet...
Ocean Sounds During ROP Exams Improve Physiology, Pain, and Comfort in Preemies
Premature infants undergoing retinopathy of prematurity (ROP) screening can experience repeated stress responses during examinations—an issue that matters because even brief discomfort may amplify physiological...
De-escalation Trials in Multiple Myeloma: Advances From Past to Future
Multiple myeloma (MM) treatment is entering a “de-escalation” era: clinicians aim to preserve deep, durable disease control while lowering long-term toxicity and treatment burden. As...
Pulsed Laser Engineering of Sulfur Defects in ZnIn2S4 Boosts CO2 Reduction
Scientists are racing to mimic photosynthesis by turning carbon dioxide (CO₂) into fuels and chemicals using sunlight. A major bottleneck in photocatalysis is finding materials...
Roadmap to Perfect Contacts in 2D Electronics, Breaking Key Barriers
Atomically thin electronics are inching toward a breakthrough—and the bottleneck is not the channel, but the contact. In graphene and transition metal dichalcogenides (TMDs), the...
Insilico Medicine Earns FDA Fast Track for AI Pan-TEAD Inhibitor ISM6331 in Mesothelioma
Insilico Medicine has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation to ISM6331, an investigational pan-TEAD inhibitor being developed...
American College of Lifestyle Medicine urges remission as chronic disease goal
ST. LOUIS—The American College of Lifestyle Medicine (ACLM) has launched Project Remission, a new initiative urging healthcare systems to rethink chronic disease goals. Rather than...