Efficient oligonucleotide synthesis is the bottleneck behind many modern applications, from molecular diagnostics to nucleic acid therapeutics. The current workhorse approach—P(III)-phosphoramidite chemistry—delivers speed and reliability,...
MINNEAPOLIS / ST. PAUL (07/29/2026) — A team at the University of Minnesota Twin Cities reports a chemical tweak that could make polylactide (PLA), a...
Kinase-driven phosphorylation is a central switch in cell signaling, yet most sites in the human proteome remain poorly characterized. Among the roughly 1.8 million serine,...
A new multi-omic study has mapped how the human testicular niche remodels when androgen signaling is abruptly removed, offering a molecular view of what Sertoli...
Brazil’s long coastline and rich marine life should, in theory, make seafood a nutritional powerhouse. Yet a new nationwide analysis suggests that the country’s seafood...
A new study in Colombia is using a sophisticated statistical lens to map how older adults perceive the age-friendliness of their cities and communities—and what...
A new multi-site study published in Gene Therapy reports that two streamlined assays—SACF and GILA—can improve how scientists evaluate whether CRISPR/Cas9-edited cell therapy candidates undergo...
Hospitals are not only places where childhood cancer is treated—they also generate records of earlier health encounters. A new population-based study now asks whether patterns...
CHAMPAIGN, Ill. — Researchers at the University of Illinois Urbana-Champaign report that a precision gene-editing strategy can reduce the toxic protein burden and neurological symptoms...
Osaka, Japan—Optimization is the quiet engine behind everything from planning transport routes to organizing huge datasets. But as these problems grow, the brute-force search through...
Aperiodic order is back in the spotlight. A team at the Institute of Industrial Science, The University of Tokyo has engineered optical structures inspired by...
A new preclinical study published in Nature Communications reports a tailored nanomedicine strategy aimed at treating hyperuricemia and its downstream complications in mice. The work...
A new approach dubbed ProteinGuide aims to let researchers steer protein sequence generative models using auxiliary experimental or user-specified information—without the heavy burden of retraining...
Mitochondria have long been treated as cellular powerhouses, but a new study reframes them as potential vehicles for targeted cancer therapy. Researchers report that mitochondria-derived...
In diabetic cardiomyopathy, the heart’s energy balance and stress-handling systems deteriorate even when blood glucose is managed. A new study now points to a molecular...
