• HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Tuesday, January 19, 2021
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home Cardiology

Obstructive sleep apnoea puts a strain on the heart, too

Bioengineer by Bioengineer
December 10, 2020
in Cardiology, Circadian Rhythm, Health, Medicine & Health, Medicine/Health, Neurobiology
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: UEF / Raija Törrönen

Longer nocturnal respiratory events in patients with obstructive sleep apnoea (OSA) cause higher immediate heart rate variability, and greater changes in beat-to-beat intervals are associated with reduced daytime alertness, according to new research from the University of Eastern Finland.

Obstructive sleep apnoea affects approximately 1 billion people worldwide. It is one of the most prevalent sleeping disorders, putting a great strain on national economies and on public health. Nocturnal respiratory events, be they complete or partial blocking of the airways, often cause repeated oxygen desaturations and interrupted sleep in patients with OSA, leading to abnormal nervous system function.

Abnormal hyperactivation of the sympathetic nervous system affects heart function and cardiovascular regulation by increasing OSA patients’ nocturnal heart rate and by reducing their long-term heart rate variability. These changes have been shown to significantly increase the risk of cardiovascular diseases. In addition, hyperactivation of the sympathetic nervous system can prevent patients with OSA from getting enough deep, restorative sleep, which is why they often feel tired and less alert during the day. Hyperactivation of the sympathetic nervous system can keep the body in a state of alertness over the long term despite sufficient deep sleep, and this can be seen in, e.g., elevated daytime heart rate in patients with OSA.

Two recent studies from the University of Eastern Finland have explored the immediate effect of respiratory events on heart rate variability, as well as the association of OSA patients’ nocturnal heart rate changes with their alertness.

A study published in Scientific Reports yesterday shows that the type and duration of individual respiratory events has an effect on heart rate and heart rate variability both during and after the event. A longer duration of a respiratory event caused greater changes in heart rate as well as higher ultra-short-term heart rate variability, and both of these changes were greater during complete obstruction of the airway.

“The study sheds important new light on the cardiovascular load nocturnal respiratory events cause in patients with OSA,” the study’s lead author Early Stage Researcher Salla Hietakoste from the University of Eastern Finland says.

The other study, published in ERJ Open Research earlier this year, found that changes in pulse rate measured via finger photoplethysmogram were associated with performance in the psychomotor vigilance task (PVT) in patients with OSA. Patients who performed poorly in the PVT had a significantly higher nocturnal heart rate.

“By taking a better look at polysomnography data for respiratory events and heart function, we might be able to identify patients who have a higher risk for reduced vigilance and alertness,” Postdoctoral Researcher Samu Kainulainen from the University of Eastern Finland says.

In both studies, the findings were more pronounced in men. The findings suggest that the abundance of data available from current clinical sleep studies could be utilised more extensively in the future. Data relating to heart rate and heart rate variability could possibly be used alongside the current diagnostic parameters for OSA in order to get a more representative clinical picture and to better identify high-risk patients.

###

The studies have received funding from the Academy of Finland, Business Finland, Kuopio University Hospital, Seinäjoki Central Hospital, Tampere University Hospital, Alfred Kordelin Foundation, the Research Foundation of the Pulmonary Diseases, Instrumentarium Science Foundation, Kuopio Area Respiratory Foundation, Orion Research Foundation, Paulo Foundation, Päivi & Sakari Sohlberg Foundation, the Finnish Cultural Foundation, the Finnish Anti-Tuberculosis Association Foundation, and Tampere Tuberculosis Foundation.

For further information, please contact:

Early Stage Researcher Salla Hietakoste, MSc, tel. +358 40 588 1975, salla.hietakoste (a) uef.fi

Postdoctoral Researcher Samu Kainulainen, PhD, tel. +358 45 641 6754, samu.kainulainen (a) uef.fi

Docent, Senior Researcher Sami Myllymaa, PhD, tel. +358 40 557 2499, sami.myllymaa (a) uef.fi

Sleep Technology and Analytics Group, https://www.uef.fi/fi/web/stag/

Research articles:

Hietakoste et al, Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea, Scientific Reports, 2020; 10: 21556. https://doi.org/10.1038/s41598-020-77780-x

Kainulainen et al, Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task, ERJ Open Research, 2020; 6: 00277-2020. https://doi.org/10.1183/23120541.00277-2020

Media Contact
Salla Hietakoste
[email protected]

Related Journal Article

http://dx.doi.org/10.1038/s41598-020-77780-x

Obstructive sleep apnoea puts a strain on the heart, too

Share12Tweet7Share2ShareShareShare1

Related Posts

IMAGE

Lasers & molecular tethers create perfectly patterned platforms for tissue engineering

January 18, 2021
IMAGE

Smart vaccine scheme quick to curb rabies threat in African cities

January 18, 2021

New computational tool reliably differentiates between cancer and normal cells from single-cell RNA-sequencing data

January 18, 2021

Timing is of the essence when treating brain swelling in mice

January 18, 2021
Next Post
IMAGE

Lung ultrasounds could help determine COVID-19 outcome

IMAGE

A biased evaluation of employees’ performance can be useful for employers

Leave a Reply Cancel reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

POPULAR NEWS

  • IMAGE

    The map of nuclear deformation takes the form of a mountain landscape

    53 shares
    Share 21 Tweet 13
  • Blood pressure drug may be key to increasing lifespan, new study shows

    44 shares
    Share 18 Tweet 11
  • New drug form may help treat osteoporosis, calcium-related disorders

    39 shares
    Share 16 Tweet 10
  • People living with HIV face premature heart disease and barriers to care

    58 shares
    Share 23 Tweet 15

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Tags

BiologyMaterialsGeneticsPublic HealthCell BiologyInfectious/Emerging DiseasescancerTechnology/Engineering/Computer ScienceMedicine/HealthClimate ChangeChemistry/Physics/Materials SciencesEcology/Environment

Recent Posts

  • Lasers & molecular tethers create perfectly patterned platforms for tissue engineering
  • Latch, load and release: Elastic motion makes click beetles click, study finds
  • Smart vaccine scheme quick to curb rabies threat in African cities
  • How cells move and don’t get stuck
  • Contact Us

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

Welcome Back!

Login to your account below

Forgotten Password?

Create New Account!

Fill the forms below to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In