• HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Sunday, January 17, 2021
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Cancer

New research paves the way for improved individual treatment of patients with cancer

Bioengineer by Bioengineer
June 17, 2016
in Cancer
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram
IMAGE

Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed. For many years, this patient group will be examined frequently and during this time many get new tumours; some cases develop aggressively making it necessary to remove the bladder or receive chemotherapy.

A research team from Aarhus University Hospital and Aarhus University headed by professor Torben Ørntoft and professor Lars Dyrskjøt has been in charge of a larger European research project mapping the molecular mechanisms of early stages of bladder cancer in 460 patients in Denmark, Sweden, The Netherlands, Germany, Spain and Serbia. The researchers found that tumours can be divided into three primary classes with very different molecular and disease-developing characteristics. These findings may be important in risk assessment and subsequent choice of treatment.

The researchers found that bladder tumours from the molecular group with high risk of developing aggressive disease contain mutations in genes and molecular pathways often associated with later stages of the disease. Moreover, the researchers observed changes in genes involved in genome structure regulation in 86% of the tumours. This new knowledge can facilitate use of new drugs targeted at these specific changes.

“This study provides new and valuable insight into the biology of the tumours in the earliest stages of the disease. Clinical and pathological examinations of the individual tumours do not always reflect the risk of later disease aggressiveness. This study provides a tool for risk assessment of the patients and thus for providing optimal treatment”, says professor Lars Dyrskjøt from Department of Molecular Medicine, Aarhus University Hospital.

###

The research results will be published in the prestigious scientific journal Cancer Cell:

Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. Hedegaard J, Lamy P, Nordentoft I, Algaba F, Høyer S, Ulhø BP3, Vang S, Reinert T, Hermann GG, Mogensen K, Thomsen MBH, Nielsen MM, Marquez M, Segersten U, Aine M, Höglund M, Birkenkamp-Demtröder K, Fristrup N, Borre M, Hartmann A, Stöhr R, Wach S, Keck B, Seitz AK, Nawroth R, Maurer T, Tulic T, Simic T, Junker K, Horstmann M, Harving N, Petersen AC, Calle ML, Steyerberg EW, Beukers W, van Kessel K, Jensen JB, Pedersen JS, Malmström PU, Malats N, Real FX, Zwarthoff EC, Ørntoft TF, and Dyrskjøt L. Cancer Cell 30, 1-16, July 11, 2016

Media Contact

Lars Dyrskjøt
[email protected]
45-42-27-19-73
@auhdk

http://www.en.auh.dk

The post New research paves the way for improved individual treatment of patients with cancer appeared first on Scienmag.

Share12Tweet7Share2ShareShareShare1

Related Posts

IMAGE

Tool that predicts if chemotherapy will produce debilitating side effects in older adults

January 14, 2021
IMAGE

New insights into pancreatitis

January 14, 2021

Bladder cancer — When to use chemotherapy

January 14, 2021

Study shows sharp decline in cancer screenings, diagnoses during the first COVID-19 surge

January 14, 2021
Next Post
blank

Researchers open hairy new chapter in 3-D printing

blank

High-tech scans can spare lymphoma patients intensive chemo

Leave a Reply Cancel reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

POPULAR NEWS

  • IMAGE

    The map of nuclear deformation takes the form of a mountain landscape

    53 shares
    Share 21 Tweet 13
  • Blood pressure drug may be key to increasing lifespan, new study shows

    44 shares
    Share 18 Tweet 11
  • New drug form may help treat osteoporosis, calcium-related disorders

    38 shares
    Share 15 Tweet 10
  • New findings help explain how COVID-19 overpowers the immune system

    35 shares
    Share 14 Tweet 9

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Tags

Climate ChangeChemistry/Physics/Materials SciencesBiologyInfectious/Emerging DiseasesTechnology/Engineering/Computer ScienceMedicine/HealthEcology/EnvironmentMaterialsGeneticscancerPublic HealthCell Biology

Recent Posts

  • Better diet and glucose uptake in the brain lead to longer life in fruit flies
  • Rapid blood test identifies COVID-19 patients at high risk of severe disease
  • Conductive nature in crystal structures revealed at magnification of 10 million times
  • Howard University professor to receive first Joseph A. Johnson Award
  • Contact Us

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

Welcome Back!

Login to your account below

Forgotten Password?

Create New Account!

Fill the forms below to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In