• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Monday, August 25, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Cancer

New research paves the way for improved individual treatment of patients with cancer

Bioengineer by Bioengineer
June 17, 2016
in Cancer
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram
IMAGE

Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed. For many years, this patient group will be examined frequently and during this time many get new tumours; some cases develop aggressively making it necessary to remove the bladder or receive chemotherapy.

A research team from Aarhus University Hospital and Aarhus University headed by professor Torben Ørntoft and professor Lars Dyrskjøt has been in charge of a larger European research project mapping the molecular mechanisms of early stages of bladder cancer in 460 patients in Denmark, Sweden, The Netherlands, Germany, Spain and Serbia. The researchers found that tumours can be divided into three primary classes with very different molecular and disease-developing characteristics. These findings may be important in risk assessment and subsequent choice of treatment.

The researchers found that bladder tumours from the molecular group with high risk of developing aggressive disease contain mutations in genes and molecular pathways often associated with later stages of the disease. Moreover, the researchers observed changes in genes involved in genome structure regulation in 86% of the tumours. This new knowledge can facilitate use of new drugs targeted at these specific changes.

“This study provides new and valuable insight into the biology of the tumours in the earliest stages of the disease. Clinical and pathological examinations of the individual tumours do not always reflect the risk of later disease aggressiveness. This study provides a tool for risk assessment of the patients and thus for providing optimal treatment”, says professor Lars Dyrskjøt from Department of Molecular Medicine, Aarhus University Hospital.

###

The research results will be published in the prestigious scientific journal Cancer Cell:

Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. Hedegaard J, Lamy P, Nordentoft I, Algaba F, Høyer S, Ulhø BP3, Vang S, Reinert T, Hermann GG, Mogensen K, Thomsen MBH, Nielsen MM, Marquez M, Segersten U, Aine M, Höglund M, Birkenkamp-Demtröder K, Fristrup N, Borre M, Hartmann A, Stöhr R, Wach S, Keck B, Seitz AK, Nawroth R, Maurer T, Tulic T, Simic T, Junker K, Horstmann M, Harving N, Petersen AC, Calle ML, Steyerberg EW, Beukers W, van Kessel K, Jensen JB, Pedersen JS, Malmström PU, Malats N, Real FX, Zwarthoff EC, Ørntoft TF, and Dyrskjøt L. Cancer Cell 30, 1-16, July 11, 2016

Media Contact

Lars Dyrskjøt
[email protected]
45-42-27-19-73
@auhdk

http://www.en.auh.dk

The post New research paves the way for improved individual treatment of patients with cancer appeared first on Scienmag.

Share12Tweet8Share2ShareShareShare2

Related Posts

TACE versus Combined TACE and Ablation for Liver Tumors

August 25, 2025
blank

Chrysin Blocks Therapy-Induced Breast Cancer Senescence

August 25, 2025

Assessing Metatarsus Adductus Angle: Reliability Study

August 25, 2025

Researchers Identify Novel ‘3D Genome Organizer’ Associated with Fertility and Cancer

August 25, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    141 shares
    Share 56 Tweet 35
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    81 shares
    Share 32 Tweet 20

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Star Apple Oil: Composition and Antimicrobial Power

Revamping EDE-Q and CIA for Inpatient Care

Linking Surrogate Endpoints to Outcomes in IgA Nephropathy

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.