• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Monday, October 27, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Cancer

New insights into how fatty liver disease progresses to cancer

Bioengineer by Bioengineer
April 7, 2019
in Cancer
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Alcoholic and non-alcoholic fatty liver disease likely take different paths to liver cancer; findings could lead to new cancer prevention strategies

Orlando, Fla. (April 7, 2019) – The buildup of fat in the liver known as fatty liver disease sometimes leads to hard-to-treat liver cancer. Scientists don’t understand why the cancer risk is higher for fatty liver disease caused by excessive alcohol consumption than for non-alcoholic fatty liver disease, which is associated with obesity and type 2 diabetes.

New research has uncovered important differences in the biological pathways that lead to cancer for alcoholic fatty liver disease compared to non-alcoholic fatty liver disease. The findings could benefit the more than 3 million people diagnosed with fatty liver disease each year.

“We want to find out the key factors and pathways that lead to liver cancer in fatty liver patients so we can slow or even prevent the liver cancer,” said Yue Jia, MD, PhD, a pathology resident at the Harbor-UCLA Medical Center who conducted the study. “It is estimated that this type of liver cancer is responsible for 250,000 to 1 million deaths each year.”

Jia will present the research at the American Society for Investigative Pathology annual meeting during the 2019 Experimental Biology meeting to be held April 6-9 in Orlando, Fla.

In the new study, the researchers examined expression levels of proteins in liver biopsies from a group of patients with alcoholic fatty liver disease and a group with non-alcoholic fatty liver disease. The proteins studied are involved in epigenetic regulation, which controls gene expression, and inflammation, which plays an important role in the disease.

The researchers observed that the two groups of patients showed significant differences in the expression of proteins involved in epigenetic regulators and inflammation. Importantly, these differences matched the ratio of liver cancer development seen for the two groups.

“If, through additional studies, we can prove that the molecules and pathways we identified modulate liver cancer development in the alcoholic fatty liver disease or non-alcoholic fatty liver disease patients, it may help identify new targets for preventing or reducing the risk of liver cancer that arises from other liver disease,” said Jia.

The researchers plan to perform additional experiments in animal models of fatty liver disease to learn more about how epigenetic regulation and inflammation pathways lead to liver cancer.

Yue Jia will present this research on Saturday, April 6 at 7 p.m. during the Experimental Biology Welcome Reception in Valencia Ballroom ABCD, Orange County Convention Center and on Monday, April 8, from 11:45 a.m.-12:45 p.m. in Exhibit Hall-West Hall B (poster A67 662.67) (abstract). Contact the media team for more information or to obtain a free press pass to attend the meeting.

###

About Experimental Biology 2019

Experimental Biology is an annual meeting that attracts more than 14,000 scientists and exhibitors from five host societies and more than two dozen guest societies. With a mission to share the newest scientific concepts and research findings shaping clinical advances, the meeting offers an unparalleled opportunity for exchange among scientists from across the U.S. and the world who represent dozens of scientific areas, from laboratory to translational to clinical research. http://www.experimentalbiology.org #expbio

About the American Society for Investigative Pathology (ASIP)

ASIP is a society of biomedical scientists who investigate mechanisms of disease. Investigative pathology is an integrative discipline that links the presentation of disease in the whole organism to its fundamental cellular and molecular mechanisms. ASIP advocates for the practice of investigative pathology and fosters the professional career development and education of its members. http://www.asip.org

Find more news briefs and tipsheets at: https://www.eurekalert.org/meetings/eb/2019/newsroom/

Media Contact
Anne Frances Johnson
[email protected]

Tags: BiologycancerDiet/Body WeightEating Disorders/ObesityInternal MedicineLiverMedicine/Health
Share12Tweet8Share2ShareShareShare2

Related Posts

Liver Transplants Using Grafts from Medically Assisted Death Donors Show Feasibility and Comparable Outcomes to Standard Donations

October 27, 2025

Intrahepatic Cholangiocarcinoma: Key Updates from Guidelines

October 25, 2025

Assessing Quality of Life After Neoadjuvant Therapy

October 25, 2025

New FISH-Clinical Tool Predicts Bladder Cancer Survival

October 25, 2025
Please login to join discussion

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1285 shares
    Share 513 Tweet 321
  • Stinkbug Leg Organ Hosts Symbiotic Fungi That Protect Eggs from Parasitic Wasps

    310 shares
    Share 124 Tweet 78
  • ESMO 2025: mRNA COVID Vaccines Enhance Efficacy of Cancer Immunotherapy

    196 shares
    Share 78 Tweet 49
  • New Study Suggests ALS and MS May Stem from Common Environmental Factor

    134 shares
    Share 54 Tweet 34

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Fluid Strategies in Preterm Infants with PDA

Unlocking Henna’s Healing Power: A Breakthrough Chemical from Lawsonia inermis Fights Fibrosis

ACHO: Enhancing Treatment Adherence through Digital Care

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 67 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.