• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Friday, August 22, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Minimally-invasive surgery for brain bleeds may not be better at restoring function than standard me

Bioengineer by Bioengineer
February 7, 2019
in Health
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

American Stroke Association Late Breaking News Brief – Abstract LB 4, Session MEII Thursday Main Event

HONOLULU, Feb. 7, 2019 — Minimally-invasive surgery to remove blood from the brain along with intermittent dosing of a clot-busting drug after a brain bleed may not improve function better than medical therapy but it was associated with fewer deaths, according to late breaking science presented at the American Stroke Association’s International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.

The research study – Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation (MISTIE III), which will be simultaneously published in The Lancet – tested if catheter-based removal of blood from intracerebral bleeding could improve the proportion of patients with mild to no disability at one year.

There is currently no effective surgical treatment for intracerebral hemorrhage, which is the most common type of lethal brain bleed. The MISTIE procedure avoids the damage of traditional craniotomy by using imaging to guide placement of a soft tube into the blood clot through a small hole in the skull to remove large amounts of blood and toxic blood components.

The study included 506 stroke patients (average age 62; 62 percent male) from 78 sites who were randomized to medical therapy or to a standardized, low mechanical impact procedure with suction and up to three days of gentle irrigation with the clot-busting drug alteplase. Two hundred and fifty-six patients were randomized to the MISTIE procedure and 250 to medical therapy. Functional recovery was compared at one year after stroke.

Researchers found:

    * For medium to large blood clots, the MISTIE procedure did not improve functional recovery one year after stroke.

    * Good recovery was achieved in 45 percent of MISTIE patients and 41 percent medical therapy patients.

    * 9 percent of patients in the MISTIE group died while 15 percent of the medical therapy patients died.

“The trial confirmed that removal of the blood clot using the MISTIE procedure can be done safely as compared to supportive therapy. But there was no difference in functional recovery between those in the surgery group and the medical group,” said Daniel F. Hanley, M.D., professor of Acute Neurology and director of the Division of Brain Injury Outcomes at Johns Hopkins University in Baltimore. “The trial results do suggest that patients have improved functional recovery when the blood clot size is reduced to about 3 tablespoonsful or less of blood. This will require further study, but, at a minimum, the trial data provide a sound basis to avoid limiting care in patients with large brain blood clots.”

###

Co-authors and disclosures are noted on the abstract.

The National Institute of Neurological Disorders and Stroke (NINDS) funded the study and Genentech Inc. donated alteplase.

Note: Scientific presentation is 11 a.m.Hawaii Time/4 p.m. Eastern Time, Thursday, Feb. 7, 2019.

Additional Resources:

* VIDEO: Miguel Perez-Pinzon, Ph.D., FAHA, Chair, International Stroke Conference 2019 Program Committee, offers overviews and perspective on late breaking science via downloadable Skype video (transcript provided) available on the right column of the release link https://newsroom.heart.org/news/minimally-invasive-surgery-for-brain-bleeds-may-not-be-better-at-restoring-function-than-standard-meds-but-may-lessen-deaths?preview=b3e72b43818e5645a2aa3a8127512911

* Stroke treatment options

* For more news from AHA International Stroke Conference 2019, follow us on Twitter @HeartNews #ISC19.

Statements and conclusions of study authors that are presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect association policy or position. The association makes no representation or warranty as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at https://www.heart.org/en/about-us/aha-financial-information.

About the American Stroke Association

The American Stroke Association is devoted to saving people from stroke — the No. 2 cause of death in the world and a leading cause of serious disability. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat stroke. The Dallas-based association officially launched in 1998 as a division of the American Heart Association. To learn more or to get involved, call 1-888-4STROKE or visit StrokeAssociation.org. Follow us on Facebook and Twitter.

Media Contact
Bridgette McNeill
[email protected]
214-706-1173
https://newsroom.heart.org/news/minimally-invasive-surgery-for-brain-bleeds-may-not-be-better-at-restoring-function-than-standard-meds-but-may-lessen-death

Tags: Medicine/HealthStroke
Share12Tweet7Share2ShareShareShare1

Related Posts

blank

Brain Neurons Play Key Role in Daily Regulation of Blood Sugar Levels

August 22, 2025
Simon Family Supports Stevens INI in Advancing Global Alzheimer’s Research

Simon Family Supports Stevens INI in Advancing Global Alzheimer’s Research

August 21, 2025

Consistent Sleep Patterns Linked to Enhanced Heart Failure Recovery, Study Reveals

August 21, 2025

Whole Exome Sequencing Links FANCM to ER-Negative Breast Cancer

August 21, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Molecules in Focus: Capturing the Timeless Dance of Particles

    141 shares
    Share 56 Tweet 35
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    114 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    81 shares
    Share 32 Tweet 20
  • Modified DASH Diet Reduces Blood Sugar Levels in Adults with Type 2 Diabetes, Clinical Trial Finds

    60 shares
    Share 24 Tweet 15

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

AI Uncovers ‘Self-Optimizing’ Mechanism in Magnesium-Based Thermoelectric Materials

Natural Disinfectants: Their Role in Prosthodontics and Oral Implantology

Brain Neurons Play Key Role in Daily Regulation of Blood Sugar Levels

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.