Cancer
Rare Sugar D-Allose Rewires a Mitochondrial Stress Circuit to Slow Disc Degeneration
A new study shows that the rare sugar D-allose restores mitophagy, suppresses cGAS–STING signalling and preserves the cytoprotective peptide ADM2...
How Local Tumor Destruction Could Wake Up the Whole Immune System
A new review in Medical Oncology argues that tumor ablation can act as an in situ vaccine whose systemic power...
Two-Minute Spiritual Questions Could Transform Care for Oral Cancer Patients
A new narrative review argues that structured spiritual history-taking tools such as FICA and HOPE can improve trust, mental well-being,...
Cancer Survivors Show Widening Gap Between Two Common Kidney-Function Tests, Chinese Study Finds
A three-center Chinese study finds that adults with a history of cancer are significantly more likely to show large gaps...
Single tRNA Molecule Found to Steer Prostate Cancer Between Drug Sensitivity and Resistance
Fred Hutch researchers report in Nature that a single transfer RNA, tRNA1Arg(UCU), controls whether prostate cancer cells remain androgen receptor-dependent...
When immune cells switch sides: unstable T cells drive gum disease bone loss
A new review argues that periodontitis is driven less by bacteria than by the plasticity and instability of CD4+ T...
Gene Variants That Detoxify Tobacco Carcinogens Reshape Oral Cancer Risk
A critical review of 21 studies finds that inherited variants in carcinogen-metabolizing enzymes, especially GSTM1 and GSTT1 null genotypes, modulate...
Money, Not Medicine: Economic Instability Keeps Female Cancer Survivors From the Care They Need
A decade of Maryland survey data shows that unemployment, low income, and renting each sharply reduce the odds that female...
Children’s Heart Tests Rely on Adult Data, Global Survey Finds
A global IFCC survey finds that most laboratories testing children for cardiac troponin rely on adult reference intervals, leaving pediatric...
Radiofrequency Ablation Shows Promise for Thyroid Tumors in High-Risk Spots
A retrospective cohort study of 268 patients found that radiofrequency ablation of small papillary thyroid carcinomas in high-risk neck locations...
Chromatin maps reveal two hidden states driving colorectal cancer
A new review synthesizes single-cell chromatin accessibility studies showing that colorectal cancer is organized into two epigenomic states whose regulatory...
From Ancient Rocks to Cancer Wards: Stable Isotopes Emerge as Mechanistic Biomarkers
A new review argues that stable isotope fractionation patterns, long used to reconstruct Earth's history, could become mechanistic biomarkers for...
Brain Tumor Survivors Map Their Shifting Symptom Journey From Diagnosis to Daily Life
A longitudinal phenomenological study of twelve Chinese glioma survivors reveals that symptom burdens, coping strategies, and care needs evolve dramatically...
Molecular Scissors: Cysteine Peptidases Emerge as Master Switches of Antitumor Immunity
A new review in iMetaMed reveals how cysteine peptidases such as cathepsins B, S, L, and X control antigen presentation...
Scientists discover a fat-burning switch that helps mice resist obesity
Researchers have identified the phosphatase DUSP4 as a key activator of fat-cell thermogenesis through dephosphorylation of CRTC3, a mechanism that...
Simple Blood Ratio Shows Promise for Spotting Aggressive Kidney and Ureter Cancer Before Surgery
A single-center study of 127 patients found that a preoperative fibrinogen-to-albumin ratio independently predicted muscle-invasive and locally advanced upper tract...
Gallic Acid Shrinks Tumors in Mice While Sparing Blood Cells, Study Finds
A new preclinical study shows that orally delivered gallic acid significantly inhibited sarcoma tumor growth in mice by suppressing proliferation,...
Immune Cells Feed Breast Cancer Tumors as AI and DNA Testing Reshape Cancer Care
New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation,...
From Therapy Dogs to Memory Training: What Really Helps Children With Cancer
A comprehensive meta-analysis of 34 trials finds that psychosocial interventions significantly improve working memory, anxiety and pain in children and...
Heatstroke Depletes a Heart-Protective Lipid, and Restoring It Saves Mice
A new mouse study shows that heatstroke depletes the anti-inflammatory lipid Maresin1 and that restoring it through the cardiomyocyte receptor...
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