Cancer

Preclinical assays found that NU7441 displaced BRD4 from acetylated chromatin and impaired homologous recombination and non-homologous end joining in ovarian...

U.S. News ranked Dana-Farber/Boston Children’s as the nation’s top pediatric cancer program based on data from 114 hospitals and surveys...

A multicenter Chinese real-world cohort found that adjuvant T-DM1 was associated with better early invasive disease-free survival than trastuzumab plus...

A meta-analysis of 21 randomised trials found that structured exercise was associated with lower mortality and recurrence risk among adults...

A Bayesian reanalysis of the RELEVANCE trial found extremely low probabilities that rituximab plus lenalidomide was inferior to rituximab plus...

A retrospective Japanese cohort study associated expanded insurance coverage for BRCA testing with a median testing interval of 54 days...

A machine learning system used dark-field scattered-light spectra to identify mesothelioma cells with about 91% accuracy in patient-based validation.

A nearly 1,800-patient international observational study found that the investigational PANXEON blood test detected 87% of stage 1 and 2...

A qualitative study of 31 breast cancer survivors identifies three trajectories of sexual recovery and highlights partner support and gaps...

A prospective study of 493 adults with newly diagnosed HIV-associated Kaposi sarcoma in East Africa found that 91% had advanced...

A cross-sectional mixed-methods study of 213 women with breast cancer in Türkiye found reported intimate partner violence in every participant...

A prospective observational study linked circulating tumor DNA fraction and copy-number burden with progression and survival in 78 patients receiving...

A mouse breast cancer study found that CD40-stimulated B cells recruited CD8+ T cells into tumors, influenced their organization and...

A qualitative study of 15 Peruvians found that hereditary cancer testing and diagnosis were shaped by faith, family networks, community...

A real-world analysis of 218 patients with metachronous metastatic nasopharyngeal carcinoma proposed a prognostic classification combining metastatic-lesion count with disease-free...

A cross-sectional study found that 36.16% of at-risk relatives underwent family-specific genetic testing, with uptake independently associated with education, family...

ASTRO’s first bladder cancer guideline recommends trimodal therapy as a curative option for selected patients and defines radiation roles after...

A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially...

The multicenter StereoBed trial will randomize 284 patients to compare five-fraction stereotactic radiotherapy with standard schedules after prostatectomy, with two-year...

A clinical trial of more than 500 cancer survivors found that mindfulness and tai chi or qigong improved pain interference,...