• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Saturday, October 4, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Bioactive implant coatings resistant to most bacterial strains are obtained in Russia

Bioengineer by Bioengineer
April 12, 2021
in Health
Reading Time: 2 mins read
0
IMAGE
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Sergey Gnuskov/ NUST MISIS

Young scientists from NUST MISIS have presented multilayer antibacterial coatings with a prolonged effect and a universal spectrum of action. The coating is based on modified titanium oxide and several antiseptic components. The coatings can be used in modern implantology as a protective layer for the prevention of concomitant complications – inflammation or implant rejection. The results of the work have been published in the international scientific journal Applied Surface Science.

Antibacterial coatings are currently being actively researched, as the search for alternatives to traditional antibiotics is growing. They can be applied to implants, thereby preventing inflammation caused by nosocomial infections.

Nevertheless, the creation of antibacterial, but at the same time biocompatible and bioactive surfaces is a problem that the scientific community has been solving for many years, and the “dream materials” have not been developed.

Young scientists from the NUST MISIS Laboratory of Inorganic Nanomaterials have created an innovative multilayer coating that synthesizes the protective properties of nanoparticles, biopolymers, anticoagulants and antibiotics. The antibiotic and silver nanoparticles provide an antibacterial effect, while heparin prevents bacterial cells from sticking to the tissue surface, which reduces the amount of antibacterial agent required.

“The method of obtaining a multilayer coating is a combination of several technologies: first, using magnetron sputtering, a thin bioactive nanostructured coating of the TiCaPCON composition was obtained, then silver particles were introduced into the coating by ion implantation, then a biopolymer layer, which plays the role of a carrier for bactericidal molecules of heparin and gentamicin in the preparation, was applied”, – said the author of the work, a researcher at the NUST MISIS Inorganic nanomaterials laboratory Elizaveta Permyakova.

The chemical composition of the resulting coating layers was carefully studied by the developers using infrared and X-ray photoelectron spectroscopy. Scientists have found out that the incorporation of therapeutic components occurs throughout the whole plasma-applied polymer layer.

Together with colleagues from the State Research Center for Applied Microbiology and Biotechnology, the scientists studied the effect of each type of the antibacterial component (silver ions, gentamicin and heparin) on the antibacterial activity and biocompatibility of the obtained coatings.

According to the results of in vitro studies, the coatings showed cellular compatibility and demonstrated excellent (up to 99%) bactericidal efficacy against the antibiotic-resistant E. coli bacterial strain.

“The combination of several bactericidal fillers and silver ions with a bioactive coating made of titanium oxide modified with calcium and phosphorus ensured biocompatibility and a long – up to 7 days – antibacterial effect of the resulting coatings,” emphasized Elizaveta Permyakova.

According to the developers, the innovative coatings can be used as an antibacterial implant modifier, allowing it to accelerate implantation by reducing the risks of associated inflammation and stimulating the growth of osteoblastic cells.

Researchers are currently planning to move to the preclinical development stage.

###

Media Contact
Lyudmila Dozhdikova
[email protected]

Related Journal Article

http://dx.doi.org/10.1016/j.apsusc.2021.149751

Tags: BiochemistryChemistry/Physics/Materials SciencesClinical TrialsHealth CareHealth Care Systems/ServicesMaterialsMedicine/HealthTransplantationTrauma/Injury
Share12Tweet8Share2ShareShareShare2

Related Posts

UmamiPredict: AI Unveils Umami Taste of Molecules

October 4, 2025

Cerebral Resistive Indices Linked to Premature Hemorrhage

October 4, 2025

Gastric Microbiome’s Role in Cancer Risk and Prognosis

October 4, 2025

Health Insurance Disparities Impact Midlife Depression Trends

October 4, 2025
Please login to join discussion

POPULAR NEWS

  • New Study Reveals the Science Behind Exercise and Weight Loss

    New Study Reveals the Science Behind Exercise and Weight Loss

    93 shares
    Share 37 Tweet 23
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    90 shares
    Share 36 Tweet 23
  • Physicists Develop Visible Time Crystal for the First Time

    75 shares
    Share 30 Tweet 19
  • New Insights Suggest ALS May Be an Autoimmune Disease

    69 shares
    Share 28 Tweet 17

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

“Rice Cultivar Transcriptome Reveals Heat Stress Response Genes”

UmamiPredict: AI Unveils Umami Taste of Molecules

Cerebral Resistive Indices Linked to Premature Hemorrhage

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 62 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.