• HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Thursday, February 25, 2021
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Advancing understanding of hop genome to aid brewers, medical researchers

Bioengineer by Bioengineer
February 22, 2021
in Health
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Oregon State University

CORVALLIS, Ore. – Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the understanding of the hop genome, a development with important implications for the brewing industry and scientists who study the potential medical benefits of hops.

“This research has the unique ability to impact several different fields,” said David Hendrix, an associate professor in the Department of Biochemistry and Biophysics and the School of Electrical Engineering and Computer Science at Oregon State. “If you’re talking to beer drinkers, they will be excited about the brewing side. If you are talking to the medical field, they are going to be excited about the pharmaceutical potential.”

The findings are outlined in a paper just published in the journal The Plant Genome. Hendrix and John Henning, a hop geneticist with the U.S. Department of Agriculture who has an appointment in the Oregon State College of Agricultural Sciences, are co-corresponding authors of the paper.

Demand for hops has surged in recent years as the craft beer industry has grown, fueled by beers, such as India pale ales, that are brewed with a lot of hops. This has led brewers to seek out new varieties of hops. With a better understanding of the hop genome, scientists will have an easier time developing new varieties, which may have qualities such as different flavor profiles or resistance to diseases that infect and damage hop plants.

“This really opens the door wide for breeding hops at the molecular level,” Henning said. “We now have a much better understanding of how traits are being controlled and what genes are involved.”

Compounds founds in hops are also increasingly of interest to medical researchers. For example, scientists at Oregon State have shown that xanthohumol, a natural flavonoid found in hops, may aid in combating cancer and metabolic syndrome. Knowing more about hop genes and how they are regulated creates potential for better understanding how compounds are produced and finding other hop compounds that could improve people’s health.

Hops are part of the Cannabaceae family of plants, which also includes hemp and marijuana. In the just-published paper, the Oregon State researchers found gene structures in the hop genome that were similar to cannabidolic acid synthase, or CBDAS, which produces the precursor structure to CBD, the compound in cannabis plants that has surged in popularity in recent years because of its potential health benefits.

The Oregon State researchers stressed that their finding doesn’t necessarily mean that hops produce CBDA, but it raises questions about the potential to identify new genes involved in the production of different compounds associated with flavoring or therapeutic benefit, and the potential to uncover new compounds in hops.

The researchers sequenced the genome of Cascade, a hop cultivar developed by USDA Agricultural Research Service in the 1960s and credited with helping to launch the craft beer movement. It is the second most widely grown hop variety in the United States today.

The United States is the top hop producing country in the world and Washington, Oregon and Idaho account for nearly all the hop acreage in the United States. In 2019, production of hops in the United States was worth more than $600 million.

Other scientists have attempted to sequence the hop genome, but they have had limited success because it is large – similar in size to the human genome – and complex, Hendrix said. The current research was made possible in part by new genome sequencing and assembly technology developed by Pacific Biosciences of California.

“The previous genomes were basically broken up,” Hendrix said. “They were sequencing a lot of the genes, but they were isolated islands of the genome and they were not really getting the full context of what was going on in those islands. We were able to reveal a more complete and continuous genomic sequence.”

###

In addition to Hendrix and Henning, the lead author on this paper was Lillian K. Padgitt-Cobb and co-authors of the paper are: Jackson Wells, Brent Kronmiller, Justin Elser and Pankaj Jaiswal, all of Oregon State; Daniel Moore of USDA Agricultural Research Service; Sarah B. Kingan, Gregory Concepcion, Paul Peluso and David Rank, all of Pacific Biosciences of California.

Funding for the sequencing was provided by Pacific Biosciences of California and Sierra Nevada Brewing Company. The research was also supported by funding from the U.S. Department of Agriculture.

Media Contact
Sean Nealon
[email protected]

Original Source

https://today.oregonstate.edu/news/scientists-advance-understanding-hop-genome-which-could-aid-brewers-medical-researchers

Tags: Agricultural Production/EconomicsAgricultureBioinformaticsBiologycancerFood/Food ScienceGeneticsMedicine/HealthMetabolism/Metabolic DiseasesPlant Sciences
Share12Tweet8Share2ShareShareShare2

Related Posts

IMAGE

New ONC, NLM funding supports data exchange and response to COVID-19 pandemic

February 25, 2021
IMAGE

Salk Professors Satchin Panda and Tatyana Sharpee honored with endowed chairs

February 25, 2021

New treatment location challenges thoughts on addiction

February 25, 2021

Male lyrebirds create an “acoustic illusion” to snare potential mates

February 25, 2021

Leave a Reply Cancel reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

POPULAR NEWS

  • IMAGE

    Terahertz accelerates beyond 5G towards 6G

    637 shares
    Share 255 Tweet 159
  • People living with HIV face premature heart disease and barriers to care

    81 shares
    Share 32 Tweet 20
  • Global analysis suggests COVID-19 is seasonal

    37 shares
    Share 15 Tweet 9
  • HIV: an innovative therapeutic breakthrough to optimize the immune system

    35 shares
    Share 14 Tweet 9

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Tags

Public HealthcancerChemistry/Physics/Materials SciencesEcology/EnvironmentTechnology/Engineering/Computer ScienceCell BiologyBiologyMedicine/HealthGeneticsMaterialsClimate ChangeInfectious/Emerging Diseases

Recent Posts

  • New ONC, NLM funding supports data exchange and response to COVID-19 pandemic
  • Toronto’s COVID-19 bike lane expansion boosted access to jobs, retail
  • Salk Professors Satchin Panda and Tatyana Sharpee honored with endowed chairs
  • New treatment location challenges thoughts on addiction
  • Contact Us

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

Welcome Back!

Login to your account below

Forgotten Password?

Create New Account!

Fill the forms below to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In