• HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Monday, January 18, 2021
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Immunology

Where you live shapes your immune system more than your genes

Bioengineer by Bioengineer
September 30, 2016
in Immunology
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Like fingerprints, immune systems vary from person to person. And although we all inherit a unique set of genes that help us respond to infections, recent studies have found that our history and environment — like where and with whom we live — are responsible for 60% to 80% of the differences between individual immune systems, while genetics account for the rest. In a Review published September 29 in Trends in Immunology, three immunologists discuss the emerging science of what shapes our immune systems and how it might be applied.

defense

“Just like it took a while to crack the genetic code, we’re finally starting to crack the immune code, and we’re shifting away from the simplistic idea that there is only one type of immune system,” says lead author Adrian Liston, head of the VIB-KU Leuven Translational Immunology Laboratory in Belgium. “Diversity isn’t just programmed into our genes — it emerges from how our genes respond to the environment.”

Long-term infections are responsible for most of the differences between individual immune systems. For example, when a person has herpes or shingles, the virus has more opportunities to interact with the immune system. These interactions slowly change the cellular makeup of their immune system and make it more sensitive to that specific virus but also easier for other infections to slip past its defenses. People without these infections don’t experience these cellular changes, and even with the occasional cold or fever, their immune systems stay relatively stable over time.

The exception is when a person is elderly. Researchers haven’t determined exactly why age plays a major role in making our individual immune systems more unique, but they have shown that aging changes how our immune system responds to threats. As we get older, an organ called the thymus gradually stops producing T cells, which are made to help to fight off infection. Without new T cells, older people are more likely to get sick and less likely to respond to vaccines.

Beyond T cells, aging also seems to broadly change the way our immune systems react. “A lot of diseases that we associated with aging have an inflammatory component, which suggests there is likely immune involvement,” says Michelle Linterman, a researcher at the Babraham Institute and co-author of the review. “Understanding how the immune system changes with age is going to be hugely important for treating age-related diseases in the future.”

Differences can be overcome, however; studies of people living together have shown that air quality, food, stress levels, sleep patterns, and lifestyle choices had a strong combined effect on our immune responses. For example, couples who cohabitate have more similar immune systems compared to the general public.

Liston and his collaborators, Linterman and Edward Carr of the Babraham Institute, would next like to explore how changing our environment could purposefully shape our immune system and potentially affect our health. “In order to tinker with the immune code, we first need to really understand the influences that shape the immune system,” says Liston. “That’s why it’s actually great that environment is more important than genetics, because we can play with environment.”

Web Source: VIB – Flanders Interuniversity Institute for Biotechnology.

Journal Reference:

Liston, Linterman, and Carr. Shaping variation in the human immune system. Trends in Immunology, September 2016 DOI: 10.1016/j.it.2016.08.002

The post Where you live shapes your immune system more than your genes appeared first on Scienmag.

Share12Tweet8Share2ShareShareShare2

Related Posts

IMAGE

Where COVID-19 hit hardest, sudden deaths outside the hospital increased

January 18, 2021
IMAGE

NIH scientists identify nutrient that helps prevent bacterial infection

January 15, 2021

SARS-CoV-2 antibody test helps select donor blood samples for therapeutic use

January 14, 2021

Scientists identify “immune cop” that detects SARS-CoV-2

January 12, 2021
Next Post
blank

Game theory research reveals fragility of common resources

Structure of the BinAB toxin revealed

Leave a Reply Cancel reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

POPULAR NEWS

  • IMAGE

    The map of nuclear deformation takes the form of a mountain landscape

    53 shares
    Share 21 Tweet 13
  • Blood pressure drug may be key to increasing lifespan, new study shows

    44 shares
    Share 18 Tweet 11
  • New drug form may help treat osteoporosis, calcium-related disorders

    39 shares
    Share 16 Tweet 10
  • People living with HIV face premature heart disease and barriers to care

    56 shares
    Share 22 Tweet 14

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Tags

Chemistry/Physics/Materials SciencesTechnology/Engineering/Computer ScienceCell BiologycancerPublic HealthMaterialsClimate ChangeGeneticsEcology/EnvironmentMedicine/HealthBiologyInfectious/Emerging Diseases

Recent Posts

  • Eliminating microplastics in wastewater directly at the source
  • Where COVID-19 hit hardest, sudden deaths outside the hospital increased
  • Many parents say teens with anxiety, depression may benefit from peer confidants at school
  • Scientists shed light on how and why some people report “hearing the dead”
  • Contact Us

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

Welcome Back!

Login to your account below

Forgotten Password?

Create New Account!

Fill the forms below to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In