• HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
Thursday, June 30, 2022
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
  • HOME
  • NEWS
    • BIOENGINEERING
    • SCIENCE NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • FORUM
    • INSTAGRAM
    • TWITTER
  • CONTACT US
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Biology

Unravelling the diversity of the wild house mouse

Bioengineer by Bioengineer
June 14, 2022
in Biology
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Scientists have revealed the genetic structure and diversity, and inferred the population history, of the wild house mouse across Europe and Asia.

Mus musculus

Credit: Toyoyuki Takada

Scientists have revealed the genetic structure and diversity, and inferred the population history, of the wild house mouse across Europe and Asia.

The house mouse, Mus musculus, is the most common rodent and is found across the world. While it is most commonly considered a pest, it has also been domesticated as the pet mouse and laboratory mouse. Laboratory mice have been invaluable to medical and genetics research as a model animal, and have been subject to intensive research, including genomic sequencing. However, the wild house mouse has not been subject to the same level of research.

A team of researchers, led by Associate Professor Naoki Osada at Hokkaido University, has conducted an analysis of whole genome sequences of wild house mice from across Europe and Asia, focusing on East, Southeast, and South Asia. Their findings, published in the journal Genome Biology and Evolution, will facilitate future biomedical and evolutionary research.

Prior research into wild house mice has revealed that, genetically, they are highly diverse. There are three primary subspecies:  M. m. musculus from northern Eurasia, M. m. castaneus from southern and southeast Asia, and M. m. domesticus from western Europe. The inbred variants of laboratory mice represent only a small fraction of the diversity of the wild house mouse.

For this study the team sequenced the whole genomes of 98 wild house mice from across Europe and Asia, collected by Dr. Kazou Moriwaki at the National Institute of Genetics, Japan. They then analysed the whole genome sequences of 121 wild house mice. They confirmed that wild house mice have a greater genetic diversity than humans. In addition, castaneus has the greatest diversity among the three subspecies. Samples from Japan and China showed the highest degrees of interbreeding between the castaneus and musculus subspecies.

The team also reconstructed the population history of the three subspecies. They estimated that the three subspecies diverged 187,000–247,000 years ago, the most recent being the castaneus and musculus split. They also inferred that the dosmesticus and musculus subspecies experienced strong population bottlenecks and expansions in the recent past, which were likely associated with the spread of agriculture.

This study illustrates the genetic diversity of wild house mice across East, Southeast, and South Asia, which had not previously been well studied. In particular they revealed that the extent and geographic range of interbreeding between the subspecies was greater than previously thought, and likely occurred after their spread alongside humans. This will significantly contribute to the understanding of mice models.

“As the lab mouse was bred from wild house mice, our study paves the way for significantly increasing the understanding of mice models,” says Naoki Osada.



Journal

Genome Biology and Evolution

DOI

10.1093/gbe/evac068

Method of Research

Experimental study

Subject of Research

Animals

Article Title

Insights into Mus musculus Population Structure across Eurasia Revealed by Whole-Genome Analysis

Article Publication Date

7-May-2022

COI Statement

The authors declare there is no conflict of interest.

Share12Tweet7Share2ShareShareShare1

Related Posts

Male evening grosbeak

Oregon State survey suggests charismatic songbird’s numbers have dramatically declined

June 29, 2022
Reconstructed sea bed scenes

Shrimps and worms among first animals to recover after largest mass extinction

June 29, 2022

Major chords and melodies may not universally be perceived as happier than minor music, according to study of remote Papua New Guinea communities

June 29, 2022

NUS research brings new light to unsolved genetic diseases in children

June 29, 2022

POPULAR NEWS

  • Pacific whiting

    Oregon State University research finds evidence to suggest Pacific whiting skin has anti-aging properties that prevent wrinkles

    37 shares
    Share 15 Tweet 9
  • University of Miami Rosenstiel School selected for National ‘Reefense’ Initiative focusing on Florida and the Caribbean

    35 shares
    Share 14 Tweet 9
  • Saving the Mekong delta from drowning

    37 shares
    Share 15 Tweet 9
  • Sharks may be closer to the city than you think, new study finds

    34 shares
    Share 14 Tweet 9

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Tags

Weather/StormsZoology/Veterinary ScienceVirologyVirusVaccineViolence/CriminalsWeaponryUrogenital SystemUniversity of WashingtonUrbanizationVehiclesVaccines

Recent Posts

  • The art of getting DNA out of decades-old pickled snakes
  • Clashes of inference and perspective explain why children sometimes lose the plot in conversation
  • The pair of Orcas deterring Great White Sharks – by ripping open their torsos for livers
  • New research: Up to 540,000 lives could be saved worldwide by targeting speed and other main areas
  • Contact Us

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

© 2019 Bioengineer.org - Biotechnology news by Science Magazine - Scienmag.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
Posting....