Tag: tumor suppression

A new study reveals that BCAT1 acts as a tumor suppressor in pancreatic adenocarcinoma by promoting the BTRC-dependent degradation of ...

A laboratory study shows TMCC2 suppresses osteosarcoma growth across cellular and mouse models while correlating with M1-like macrophage responses.

Knocking down CISD2 suppresses gastric cancer cell growth and induces ferroptosis through inhibition of the mTOR/SREBF1/SCD1 axis and GPX4 downregulation, ...

A new narrative review synthesizes how the multifunctional protein JWA intersects with redox homeostasis across cancer, neurodegeneration and tissue injury, ...

A combined bioinformatics and experimental study finds that the potassium channel KCNH8 is reduced in breast tumors and restrains triple-negative ...

A new open-access review summarizes evidence that the PARK2-encoded E3 ubiquitin ligase Parkin suppresses tumors by regulating mitochondrial function, redox ...

Skeletal muscle has long been appreciated as the body's largest organ, essential for movement, metabolism, and overall physiological stability. But ...

An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent ...

Researchers have discovered Δ246p53, a conserved 18-kilodalton p53 isoform translated from codon 246 that responds to DNA damage and enhances ...

A new PLOS Genetics study shows that the Drosophila protein Xrp1 protects genome integrity through both a p53-dependent DNA damage ...

Recent developments in cancer research have brought to light the complex mechanisms that regulate tumor growth and metastasis. Among these, ...

In a groundbreaking study set to transform ovarian cancer diagnostics and therapies, researchers have unveiled the critical role of phospholipase ...