In a murine model of pancreatic adenocarcinoma, ultrasound histotripsy and radiotherapy induced local tumor control while activating distinct myeloid and ...
An integrated pan-cancer analysis of public multi-omics data across 33 tumor types revealed that elevated FBL expression correlates with advanced ...
A scientific review highlights radio-immunomics as an emerging tool to assess hepatocellular carcinoma immune microenvironments, though the approach remains investigational ...
Researchers find that the intratumoral bacterium Comamonas testosteroni promotes cervical cancer progression by metabolizing estrogen and suppressing M1 macrophage polarization.
A comprehensive review examines how oral microbial dysbiosis promotes gastric inflammation, immune evasion, and metabolic reprogramming while highlighting novel diagnostic ...
A machine learning model identified a five-gene immune evasion signature that stratifies bladder cancer survival and associates with immunotherapy response ...
A scientific review outlines how copper-induced mitochondrial proteotoxicity could trigger innate immune sensing to counteract immunosuppressive microenvironments in glioblastoma.
Silencing HLA-DMA curbs glioblastoma cell malignancy and remodels tumor macrophages while enhancing anti-PD-1 immunotherapy efficacy in preclinical models.
An integrated transcriptomic and functional investigation identifies a seven-lncRNA program linked to SLC7A11 that correlates with advanced disease, immune remodeling, ...
Researchers identified a DDX3X-METTL3 molecular axis that promotes glioma progression by altering the tumor immune microenvironment and macrophage infiltration.
In a multicenter study of 986 patients with esophageal squamous cell carcinoma receiving definitive chemoradiotherapy, researchers developed an interpretable CT ...
Researchers developed a validated four-gene prognostic signature for medulloblastoma based on vasculogenic mimicry that independently predicts patient overall survival and ...
A new prognostic model for hepatocellular carcinoma identifies ANGPT2 as a key driver of malignant progression and immune resistance.
Researchers evaluated PSMB7 across multiple datasets and cell lines, identifying it as an independent prognostic biomarker linked to immune microenvironment ...
Genomic analysis of 71 tumors from 20 patients shows most secondary chest lesions in head and neck squamous cell carcinoma ...
A study evaluates pulsed low-dose-rate radiotherapy and finds the spatial distance between SPP1-positive TAMs and GZMK-positive CD8-positive T cells is ...
A Phase II trial in Japan identified TCR signaling mutations and clonal hematopoiesis burden as biomarkers predicting dasatinib response in ...
A multi-cohort study finds that five genes upregulated in clear cell renal cell carcinoma mark the immune microenvironment rather than ...
A multicenter study reports a Vision Transformer-based pathology framework whose risk scores, validated in 2,552 glioma cases, predict survival and ...
A 20-gene folate metabolism signature predicted hepatocellular carcinoma survival in some cohorts but failed in another, and the glutathione synthetase ...
