Tag: therapeutic targeting

A Nature Metabolism review examines how cells balance de novo synthesis and salvage of nucleotides across tissues, immunity and cancer.

A review identifies bioenergetic state, redox balance, nutrients, metal ions, inflammatory metabolism and organelle function as major influences on regulated ...

A new review in Biogerontology argues that the Hippo–YAP/TAZ signalling pathway acts as a central hub linking brain ageing, neurodegeneration, ...

A new review in Molecular Biology Reports synthesizes evidence that NFAT1-4 transcription factors drive the abnormal proliferation of pulmonary artery ...

In a groundbreaking study, researchers have unveiled the crucial role of the ANGPTL3-integrin α5 axis in driving retinal vascular leakage, ...

In recent years, the intricate relationship between tumor cells and their surrounding microenvironment has become a focal point in cancer ...

In the rapidly evolving field of oncology, one molecule is emerging as a pivotal player in the intricate balance of ...

In a groundbreaking advancement in the realm of molecular biology and cell death, researchers have uncovered a pivotal mechanism by ...

In the rapidly evolving landscape of cellular biology, researchers continue to uncover intricate mechanisms that govern cellular function and immune ...

Recent advances in cancer and respiratory disease research have unveiled a compelling link between the hypoxia-inducible factor 1 (HIF-1) signaling ...

In a groundbreaking study that could reshape the therapeutic landscape for aggressive brain tumors, researchers have identified the amino acid ...