Tag: Sphingolipids

A matched multi-omics study of 180 children in Niger identifies extracellular matrix proteins and sphingolipid disturbances as molecular signatures of ...

A new review argues that disrupted lipid handling in astrocytes may amplify motor neuron injury and disease progression in ALS.

A targeted lipidomic study in engineered human astrocytoma cells found that Alexander disease-associated GFAP mutations caused distinct, extensive changes in ...

A review finds that microbial metabolites may influence variable responses to MASH therapies, but direct clinical evidence linking gut microbial ...

A comprehensive evolutionary analysis of sphingolipid metabolism proteins across the fungal tree of life reveals that gene duplications in key ...

Precise mutations in the fruit fly's sole ceramide synthase either worsen or partially ease high-sugar-diet insulin resistance, linking sphingolipid composition ...

A multi-omics study has mapped stage-specific lipid remodeling across human stem cell differentiation into cardiomyocytes, revealing that polyunsaturated phospholipids accumulate ...

Researchers have identified the lipid sphingomyelin (30:1; O2) as a blood-based biomarker that outperforms conventional tumor markers in distinguishing intrahepatic ...

A multi-omics study of 67 Parkinson's disease patients and 64 controls reveals microbial-driven lipid and amino acid pathways, with gut-derived ...

A new review in Molecular Biology Reports maps how the ceramide–S1P balance and ganglioside signaling form a cancer-type-specific lipid code ...

In an exhilarating stride toward understanding lung cancer’s biochemical landscape, researchers have unveiled a complex yet compelling portrait of how ...