Study Uncovers RNA Editing Patterns in Chicken Cells During Marek’s Disease Infection
Researchers identified 642 RNA editing events in chicken CD4+ T cells, revealing distinct editing patterns associated with Marek's disease resistance.
Tag: RNA editing
First Complete Mitochondrial Genome of Star Fruit Assembled and Characterized
Researchers have assembled the first complete mitochondrial genome of star fruit, resolving its structural characteristics and phylogenetic placement in Oxalidales.
Human Argonaute 2 becomes a programmable RNA editing tool
Researchers engineered a programmable RNA base editor called ALTER from human Argonaute 2 fused to APOBEC3A, achieving stronger editing with ...
Scientists assemble the complete mitochondrial genome of Camellia pitardii
Researchers have assembled the complete 895,290-bp mitochondrial genome of Camellia pitardii, revealing repeat-driven structural plasticity, extensive C-to-U RNA editing and ...
Circular RNA aptamers recruit natural ADAR1 to edit RNA with near-perfect efficiency
A new RNA editing platform called MARRS recruits the cell's own ADAR1 enzyme with engineered circular RNA aptamers, achieving up ...
First Complete Mitochondrial Genome of Chinese Dwarf Cherry Assembled with PacBio HiFi Reads
Using PacBio HiFi long-read sequencing, researchers assembled the first complete circular mitochondrial genome of the Chinese dwarf cherry Prunus humilis, ...
First Mitochondrial Genomes Tie Endangered Hansenia Speciation to Plateau Uplift
The first complete mitochondrial genomes of endangered Hansenia species from the Qinghai-Tibet Plateau reveal varied genome architectures and link the ...
Great Burnet Mitochondrial Genome Assembled to Reveal Rosaceae Evolution
Scientists have assembled the complete mitochondrial genome of Sanguisorba officinalis, a 295,903-base-pair circular molecule whose analysis catalogues 60 genes, 460 ...
RNA editing as an epitranscriptomic immune switch in tumor immunity and cancer immunotherapy
A review in Journal of Translational Medicine describes how dysregulated RNA editing suppresses tumor immune recognition and how programmable RNA ...
RNA Tag m6A Emerges as a Master Switch in Gene Control, Stress and Disease
A review in Nature Reviews Molecular Cell Biology explains how the RNA modification N6-methyladenosine regulates gene expression, enables cellular adaptation, ...
Complete A. venetum mitogenome reveals chloroplast-derived DNA
A complete mitochondrial genome assembly for Apocynum venetum reveals 61 genes, extensive repeats and evidence of intracellular chloroplast-to-mitochondrion gene transfer.
Mitogenome architecture and evolutionary insights in Origanum vulgare: comparative analysis of structural diversity and repeat-mediated recombination
A comparative genomic study assembled and annotated the 497,243-base-pair Origanum vulgare mitogenome, identifying 57 genes, extensive repeat structure and 395 ...
Moss Genome Study Reveals Surprising RNA Editing and Codon Usage Patterns
A medicinal moss from the mountains of Yunnan, China, has delivered its complete mitochondrial genome to science for the first ...
Cesium and Glycine Switch On the Brain’s Inhibitory Glycine Receptor Through the Same Molecular Machinery, Study Finds
New mutagenesis and patch-clamp experiments reveal that cesium ions activate the RNA-edited glycine receptor α3L through the same structural framework ...
Medicinal Mushroom’s Mitochondrial Genome Reveals Conserved Core and Dynamic Evolution
The first complete mitochondrial genome of the medicinal mushroom Phellinus tuberculosus reveals a conserved core of respiratory genes alongside repeats ...
Medicinal Plant’s Mitochondrial Genome Rewrites the Rules of Shape and Stability
Scientists have assembled the complete mitochondrial genomes of four Rehmannia species, revealing dramatic structural diversity alongside remarkably conserved genes and ...
RNA-Binding Protein ADAR2 Throttles Bladder Cancer Spread by Destroying Fat-Making Enzyme Message
A new study shows that the RNA-binding protein ADAR2 suppresses bladder cancer metastasis by destabilizing FASN mRNA and curbing fatty ...
Giant Mitochondrial Genomes of Konjac Plants Revealed in Full for the First Time
Researchers have assembled the complete mitochondrial genomes of two konjac species, Amorphophallus muelleri and Amorphophallus krausei, revealing giant circular genomes, ...
Loss-of-Function ADAR Variant Triggers Bowel Inflammation
In a groundbreaking study that uncovers a new frontier in our understanding of the immune system and inflammatory diseases, researchers ...
