Deep Learning Reads Molecular Dynamics to Decode Protein Allostery
A new graph neural network framework called AlloPool distills molecular dynamics simulations into minimal, time-resolved interaction networks that reveal how ...
Tag: Protein Engineering
DyME: A New Engine Automates Thousands of Protein Simulations for Molecular Design
Researchers have developed DyME, an open-source platform that automates high-throughput mutagenesis, molecular dynamics simulation, and comparative analysis of thousands of ...
Global AI protein design contest puts 12,000 computer-made cancer binders to the test in living T cells
A global competition benchmarked 12,000 AI-designed CD20 binders in primary human CAR-T cells, revealing common design failure modes and simple ...
AI-Designed Protein Binders Face Real-World Test in Landmark CAR T Cell Competition
A crowdsourced competition called Bits to Binders tested 12,000 AI-designed minibinders as CAR T cell recognition domains, revealing both the ...
AI Meets Catalysis: A New Scientific Paradigm Is Emerging
A new bibliometric review reveals that artificial intelligence and catalysis, despite explosive individual growth, intersect in only 0.02 percent of ...
Engineering Plant Immune Receptors to Build Durable, Broad-Spectrum Crop Resistance
A new Nature Reviews Bioengineering review charts how structural biology, gene transfer and AI-assisted protein design are turning plant immune ...
AlphaFold Structures Turn Light-Sensitive Protein Variants Into Predictable Molecular Maps
Researchers have developed Foldinsight, a framework that uses AlphaFold2-predicted structures and molecular field descriptors to model and spatially interpret the ...
Rewrite Construction of complex and diverse DNA sequences using DNA three-way junctions as a headline for a science magazine post, using no more than 7 words
Sidewinder can also assemble defined diversities across a large number of positions along the entire length of a DNA sequence ...
Engineering Proteins to Reconstruct the Gut in the Laboratory
Researchers at the Institute for Bioengineering of Catalonia (IBEC) have unveiled a groundbreaking method that revolutionizes our understanding of intestinal ...
